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Analysis of survival from blood cancer in England

Status

Ongoing

Title

Analysis of survival from blood cancer in England

What is the aim of the study and why is it important?

I. To estimate the number of years of life lost due to blood cancer in England
II. To identify and measure disparities in blood cancer survival in England (by age, geographic area, gender, deprivation quintile and ethnicity)
III. To estimate potentially avoidable deaths if disparities in survival were eliminated
IV. To generate estimates of cancer survival that can be compared to survival in other UK nations (Wales, Northern Ireland, Scotland)
V. To determine how/if cancer survival disparities by ethnicity differ if cancer registry data is supplemented with primary care data
VI. To compare how blood cancers are classified between primary care records (SNOMED and ICD-10 codes) and cancer registry records (ICD-10 and ICD-O codes)

Chief Investigator

Dr Diana Withrow

Lead Applicant Organisation Name

Sponsor

Oxford

Location of research

Oxford

Date on which research approved

09-Nov-2023

Project reference ID

OX333

Generic ethics approval reference

18/EM/0400

Are all data accessed are in anonymised form?

Yes

Brief summary of the dataset to be released (including any sensitive data)

GP Practice. Demographics - age, sex, ethnicity, geographical region, GP practice, cancer diagnoses.

We are requesting the full record of the mortality data (e.g., not limited to those with an EMIS record).

Yes. The cancer registry data contain data on cancer diagnoses, histological type, grade, route to diagnosis, deprivation quintile (Income Deprivation Domain, derived from the postcode of residence at diagnosis). We are requesting the full record of the cancer registry data (e.g., not limited to those with an EMIS record).

Funding Source

Blood Cancer UK

Public Benefit Statement

Research Team

Dr Diana Withrow (University of Oxford)

Prof Julia Hippisley-Cox (University of Oxford)

Aziz Sheikh (University of Edinburgh)

Dr Christopher Cardwell (Queen's University Belfast))

Dr Emma Mi (University of Oxford)

Dr. Janice Hoang (University of Oxford)

Access Type

Trusted Research Environment (TRE)

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