Research Papers

Research Papers
Development and evaluation of clinical prediction models for risk-stratified early detection, prevention and management of breast cancer Authors: Clift A, Collins G, Dodwell D, Lord S, Petrou S Brady, J, Hippisley-Cox J https://ora.ox.ac.uk/objects/uuid:f51592ab-e92e-4075-92c7-12d2227e0cec
A protocol to assess antipsychotics prescribing and physical health monitoring in children and young people: a cohort study using primary care data from QResearch Authors: Yana Vinogradova, Ruth H Jack, ProfileVibhore Prasad, Carol Coupland, Richard Morriss, Chris Hollis https://www.medrxiv.org/content/10.1101/2024.07.18.24310326v1
Identifying early symptoms associated with a diagnosis of childhood, adolescent and young adult cancers: a population-based nested case-control study Authors: D. Saatci, J. Oke, A. Harnden, J. Hippisley-Cox https://www.nature.com/articles/s41416-024-02786-5?utm_source=rct_congratemailt&utm_medium=email&utm_campaign=oa_20240714&utm_content=10.1038/s41416-024-02786-5
Hormone replacement therapy and cancer mortality in women with 17 site-specific cancers: a cohort study using linked medical records Authors: Chris R. Cardwell, Tom A. Ranger, Alexander M. Labeit, Carol A. C. Coupland, Blánaid Hicks, Carmel Hughes,Úna McMenamin, Xue W. Mei, Peter Murchie, Julia Hippisley-Cox https://www.nature.com/articles/s41416-024-02767-8.epdf?sharing_token=0PCD9vtHy0hr5ggHagZzZ9RgN0jAjWel9jnR3ZoTv0N4fybl8UJNvY3fuD5Tl0jca6rlQTTktYkWbqC4TvjFVIhq0dnda3AgIRXeffUUg2Kgc0viFhJts5Klk06BhtsboxPo72LcWBaGZWvCu5-gWl6xyQXASKfo70XmOAkqZNY%3D
Incidence of menstrual symptoms suggestive of possible endometriosis in adolescents: and variance in these by ethnicity and socio-economic status Authors: Sharon Dixon, Katy Vincent, Jennifer Hirst, Julia Hippisley-Cox https://bjgp.org/content/74/suppl_1/bjgp24X737685
How did the COVID-19 pandemic affect cancer patients in England who had hospital appointments cancelled? Authors: Jakub Lonsky, Catia Nicodemo, Stuart Redding https://www.sciencedirect.com/science/article/pii/S0277953624004428?via%3Dihub
Uptake, efectiveness and safety of COVID-19 vaccines in individuals at clinical risk due to immunosuppressive drug therapy or transplantation procedures: a population-based cohort study in England Authors: Daniel Tzu‑Hsuan Chen1, Emma Copland, Jennifer A. Hirst, Emma Mi, Sharon Dixon, Carol Coupland, Julia Hippisley‑Cox https://link.springer.com/content/pdf/10.1186/s12916-024-03457-1.pdf
Associations between BMI and hospital resource use in patients hospitalised for COVID-19 in England: a community-based cohort study Authors: James Altunkaya, Carmen Piernas, Koen B Pouwels, Susan A Jebb, Philip Clarke, Nerys M Astbury, Jose Leal https://www.thelancet.com/journals/landia/article/PIIS2213-8587(24)00129-3/fulltext
QCOVID Risk Prediction Tool Final Report to NIHR Policy Research Programme Authors: Julia Hippisley-Cox, Carol AC Coupland, Nisha Mehta, Ruth H Keogh, Karla Diaz-Ordaz, Kamlesh Khunti, Ronan A Lyons, Frank Kee, Aziz Sheikh, Sharon Dixon, Shamim Rahman, Jonathan Valabhji, Ewen M Harrison, Peter Sellen, Nazmus Haq, Malcolm G Semple, Peter WM Johnson, Andrew Hayward, Jonathan S Nguyen-Van-Tam https://www.qresearch.org/media/qarlvbvv/qcovid-final-report-nihr-may-2024.pdf
Safety outcomes following COVID-19 vaccination and infection in 5.1 million children in England Authors: Emma Copland, Martina Patone, Defne Saatci, Lahiru Handunnetthi, Jennifer Hirst, David P. J. Hunt, Nicholas L. Mills, Paul Moss, Aziz Sheikh, Carol A. C. Coupland, Anthony Harnden, Chris Robertson, Julia Hippisley-Cox https://link.springer.com/article/10.1038/s41467-024-47745-z?utm_source=rct_congratemailt&utm_medium=email&utm_campaign=oa_20240527&utm_content=10.1038%2Fs41467-024-47745-z
Effectiveness and safety of COVID-19 vaccination in people with blood cancer Authors: Emma Copland, Jennifer Hirst, Emma Mi, Martina Patone, Daniel Chen, Carol Coupland, Julia Hippisley-Cox https://www.ejcancer.com/article/S0959-8049(24)00079-0/fulltext
Predicting the risk of pancreatic cancer in adults with new-onset diabetes: development and internal–external validation of a clinical risk prediction model Authors: Ash Kieran Clift, Pui San Tan, Martina Patone, Weiqi Liao, Carol Coupland, Rachael Bashford-Rogers, Shivan Sivakumar & Julia Hippisley-Cox https://www.nature.com/articles/s41416-024-02693-9
Development and validation of a new algorithm for improved cardiovascular risk prediction Authors: Hippisley-Cox J, Coupland CAC, Bafadhel M, Russell REK, Sheikh A, Brindle P, Channon KM https://www.nature.com/articles/s41591-024-02905-y
Mortality and adverse events associated with statin use in primary care patients with depression: a real-world, population-based cohort study Authors: De Giorgi R, De Crescenzo F, Ostinelli E, Cowen P, Harmer C, Fazel S, Fazel S https://ora.ox.ac.uk/objects/uuid:40da4ee4-1849-427c-a8a6-697deeae45ba
Exploring the interface between adolescent dysmenorrhoea and endometriosis: a protocol for a cohort and nested case-control study within the QResearch Database Authors: Dixon S, Ranger T, Burchardt J, Patone M, Snelling A, Vincent K, Hippisley-Cox J https://pubmed.ncbi.nlm.nih.gov/36787972/
Importance of accurate and accessible recording of healthcare contacts in mental health Authors: Jack RH, Coupland CAC, Joseph RM, Hollis C, Morriss R, Knaggs RD, Cipriani A, Cortese S, Hippisley-Cox J https://link.springer.com/article/10.1186/s12916-023-03044-w
Impact of vaccination on COVID-19-associated admissions to critical care in England: a study of population linked data with quantitative bias analysis for linkage error. Authors: Harrison D, Watkinson P, Doidge J, Shankar-Hari M, Mouncey P, Patone M, Coupland CAC, Hippisley-Cox J, Rowan K https://ijpds.org/article/view/1943
Analysis of primary care electronic health record data of people living with hepatitis B virus: infection and hepatocellular carcinoma risk associated with socio-economic deprivation Authors: Campbell C, Wang T, Gillespie I, Barnes E, Matthews PC https://www.sciencedirect.com/science/article/pii/S0033350623004134
Dynamic updating of clinical survival prediction models in a changing environment Authors: Tanner KT, Keogh RH, Coupland CAC, Hippisley-Cox J & Diaz-Ordaz K https://diagnprognres.biomedcentral.com/articles/10.1186/s41512-023-00163-z
Ethical and legal implications of implementing risk algorithms for early detection and screening for oesophageal cancer, now and in the future Authors: Brigden T, Mitchell C, Redrup Hill E, Hall A https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0293576
Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data Authors: Jack RH, Joseph RM, Hollis C, Hippisley-Cox J, Butler D, Waldram D, Coupland CAC https://mentalhealth.bmj.com/content/26/1/e300855.long
Uptake, effectiveness and safety of COVID-19 vaccines in the immunocompromised population: A population-based cohort study in England Authors: Chen D, Copland E, Hirst J, Mi E, Dixon S, Coupland CAC, Hippisley-Cox J https://www.researchsquare.com/article/rs-3316645/v1
Development and validation of a novel risk prediction algorithm to estimate 10-year risk of oesophageal cancer in primary care: prospective cohort study and evaluation of performance against two other risk prediction models Authors: Hippisley-Cox J, Mei W, Fitzgerald, Coupland CAC https://www.sciencedirect.com/science/article/pii/S2666776223001199?via%3Dihub
Predicting 10-year breast cancer mortality risk in the general female population in England: a model development and validation study Authors: Ash Kieran Clift MBBS, Prof Gary S Collins, Simon Lord, Prof Stavros Petrou, David Dodwell, Prof Michael Brady, Prof Julia Hippisley-Cox https://www.sciencedirect.com/science/article/pii/S2589750023001139
Risk prediction of covid-19 related death or hospital admission in adults testing positive for SARS-CoV-2 infection during the omicron wave in England (QCOVID4): cohort study Authors: Hippisley-Cox J, Khunti K, Sheikh A, Nguyen-Van-Tam JS, Coupland CAC https://www.bmj.com/content/381/bmj-2022-072976
An external validation of the QCOVID3 risk prediction algorithm for risk of hospitalisation and death from COVID-19: An observational, prospective cohort study of 1.66m vaccinated adults in Wales, UK Authors: Lyons J, Nafilyan V, Akbari A, Bedston S, Harrison E, Hayward A, Hippisley-Cox J, Kee F, Khunti K, Rahman S, Sheikh A, Torabi F, Lyons RA https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0285979
Disparities in care and outcomes for primary liver cancer in England during 2008–2018: a cohort study of 8.52 million primary care population using the QResearch database Authors: Liao W, Coupland CAC, Innes H, Jepsen P, Matthews PC, Campbell C, The DeLIVER consortium https://www.sciencedirect.com/science/article/pii/S2589537023001463
The current status of risk-stratified breast screening Authors: Clift AK, Dodwell D, Lord S, Petrou S, Brady M, Collins GS, Hippisley-Cox J https://www.nature.com/articles/s41416-021-01550-3
Development and internal-external validation of statistical and machine learning models for breast cancer prognostication: cohort study Authors: Clift AK, Dodwell D, Lord S, Petrou S, Brady M, Collins GS, Hippisley-Cox J https://www.bmj.com/content/381/bmj-2022-073800
Predicting the future risk of lung cancer: development, and internal and external validation of the CanPredict (lung) model in 19·67 million people and evaluation of model performance against seven other risk prediction models Authors: Liao W, Coupland CAC, Burchardt B, Baldwin DR, Gleeson F, Batchkala G, Buchanan J, Burchardt J, Chakraborty R, Chana R, Chen Y, Crichton C, Davies J, Devaraj A, Fan M, Hippisley-Cox J, Koleva-Kolarova R, Lee R, Nair A, Pickup L, Powell A, Rittscher J, Shadmaan A, Shanmugam K, Stokes E, Verrill C, Watkins J, Wordsworth S https://www.sciencedirect.com/science/article/pii/S2213260023000504
Uptake of COVID-19 vaccination in people with blood cancer: Population-level cohort study of 12 million patients in England Authors: Hirst J, Mi E, Copland E, Patone P, Coupland C, Hippisley-Cox J https://www.ejcancer.com/article/S0959-8049(23)00059-X/fulltext
Factors influencing influenza, pneumococcal and shingles vaccine uptake and refusal in older adults: a population-based cross-sectional study in England Authors: Tan PS, Patone M, Clift AK, Dambha-Miller H, Saatci D, Ranger TA, Garriga C, Zaccardi F, Shah BR, Coupland C, Griffin SJ, Khunti K, Hippisley-Cox J https://bmjopen.bmj.com/content/13/3/e058705.citation-tools
Estimating the epidemiology of chronic Hepatitis B Virus (HBV) infection in the UK: what do we know and what are we missing? Authors: Campbell C, Wang T, Burrow R, Mandal S, Hippisley-Cox J, Barnes E, Matthews PC https://wellcomeopenresearch.org/articles/7-203/v2
Ethnic disparities in COVID-19 outcomes: a multinational cohort study of 20 million individuals from England and Canada Authors: Zaccardi F, Pui PS, Shah BR, Everett K, Clift AK, Patone M, Saatci D, Coupland C, Griffin SJ, Khunti K, Dambha-Miller H, Hippisley-Cox J https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-023-15223-8
Analysis of uptake, effectiveness and safety of COVID-19 vaccinations in pregnancy using the QResearch database: research protocol and statistical analysis plan Authors: Emma Copland, Jennifer A Hirst, Tom Ranger, Winnie Xue Mei, Sharon Dixon, Carol Coupland, Kenneth Hodson, Jonathan Luke Richardson, Anthony Harnden, Aziz Sheikh, Carol Dezateux, Brenda Kelly, Marian Knight, Jonathan Van Tam, Alessandra Morelli, Joanne Enstone, Julia Hippisley-Cox https://www.medrxiv.org/content/10.1101/2022.12.19.22283660v1
QFracture 2016 Annual Update Information Authors: Professor Julia Hippisley-Cox, Professor Carol Coupland https://www.qresearch.org/media/qirhz3ti/qfracture-2016-annual-update-information.pdf
Preexisting Neuropsychiatric Conditions and Associated Risk of Severe COVID-19 Infection and Other Acute Respiratory Infections Authors: Tom Alan Ranger PhD, Ash Kieran Clift MBBS, Martina Patone PhD, Carol A. C. Coupland, PhD1,3; Robert Hatch, BMBCh, Karen Thomas MSc, Peter Watkinson MD, Julia Hippisley-Cox MD https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2798511?utm_campaign=articlePDF&utm_medium=articlePDFlink&utm_source=articlePDF&utm_content=jamapsychiatry.2022.3614
Uptake of COVID-19 Vaccination in People with Haematological Malignancy and Other High-Risk Blood Disorders: Cohort Analysis of 12 Million Patients in England Authors: Hirst J, Mi E, Copland E, Patone M, Coupland C, Hippisley-Cox J https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4257653
Development and validation of personalised risk prediction models for early detection and diagnosis of primary liver cancer among the English primary care population using the QResearch® database: research protocol and statistical analysis plan Authors: Weiqi Liao, Peter Jepsen, Carol Coupland, Hamish Innes, Philippa C. Matthews, Cori Campbell, Eleanor Barnes & Julia Hippisley-Cox https://diagnprognres.biomedcentral.com/articles/10.1186/s41512-022-00133-x
Uptake of Sotrovimab for prevention of severe COVID-19 and its safety in the community in England Authors: Martina Patone, Andrew JHL Snelling, Holly Tibble, Carol AC Coupland, Aziz Sheikh, Julia Hippisley-Cox https://www.medrxiv.org/content/10.1101/2022.08.17.22278893v1
Impact of vaccination on COVID-19-associated admissions to critical care in England: a population cohort study of linked data Authors: David A Harrison, Peter J Watkinson, James C Doidge, Manu Shankar-Hari, Paul R Mouncey, Martina Patone, Carol A C Coupland, Julia Hippisley-Cox, Kathryn M Rowan https://www.medrxiv.org/content/10.1101/2022.10.03.22280649v1
Ethnicity and risks of severe COVID-19 outcomes associated with glucose-lowering medications: A cohort study Authors: Francesco Zaccardi PhD, Pui San Tan PhD, Carol Coupland PhD, Baiju R. Shah PhD, Ash Kieran Clift MBBS, Defne Saatci MBBS, Martina Patone PhD, Simon J. Griffin DM, Hajira Dambha-Miller PhD, Kamlesh Khunti PhD, Julia Hippisley-Cox FRCP https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.14872
Oxcode Symposium Poster Weiqi Liao Qcancer2 DART Authors: Liao, W, Coupland C, Burchardt J, Baldwin D, Gleeson F, Hippisley-Cox J https://www.qresearch.org/media/evbkssll/oxcode-symposium-poster-weiqi-liao-qcancer2-dart-wp6.pdf
Oxcode Symposium Lightning Talk Weiqi Liao Qcancer2 DART (WP6) Authors: Liao, W https://www.qresearch.org/media/dhobcedv/oxcode-symposium-lightning-talk-weiqi-liao-qcancer2-dart-wp6.pdf
QCovid 4 - Predicting risk of death or hospitalisation from COVID-19 in adults testing positive for SARS-CoV-2 infection during the Omicron wave in England Authors: Julia Hippisley-Cox, Kamlesh Khunti, Aziz Sheikh, Jonathan S Nguyen-Van-Tam, Carol AC Coupland https://www.medrxiv.org/content/10.1101/2022.08.13.22278733v1
Risk of Myocarditis After Sequential Doses of COVID-19 Vaccine and SARS-CoV-2 Infection by Age and Sex Authors: Martina Patone, Xue W. Mei, Lahiru Handunnetthi, Sharon Dixon, Francesco Zaccardi, Manu Shankar-Hari, Peter Watkinson, Kamlesh Khunti, Anthony Harnden, Carol A.C. Coupland, Keith M. Channon, Nicholas L. Mills, Aziz Sheikh and Julia Hippisley-Cox https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.059970
Identifying key signs of motor neurone disease in primary care: a nested case–control study using the QResearch database Authors: Xue W Mei, Judith Burchardt, Tom A Ranger, Christopher J McDermott, Aleksandar Radunovic, Carol Coupland, Julia Hippisley-Cox https://bmjopen.bmj.com/content/12/6/e058383
Development and validation of a meta-learner for combining statistical and machine learning prediction models in individuals with depression Authors: Qiang Liu, Georgia Salanti, Franco De Crescenzo, Edoardo Giuseppe Ostinelli, Zhenpeng Li, Anneka Tomlinson, Andrea Cipriani, Orestis Efthimiou https://bmcpsychiatry.biomedcentral.com/track/pdf/10.1186/s12888-022-03986-0.pdf
Associations of BMI with COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes after vaccination in England: a population-based cohort study Authors: Carmen Piernas, Martina Patone, Nerys M Astbury, Min Gao, Aziz Sheikh, Kamlesh Khunti, Manu Shankar-Hari, Sharon Dixon, Carol Coupland, Paul Aveyard, Julia Hippisley-Cox, Susan A Jebb https://www.thelancet.com/action/showPdf?pii=S2213-8587%2822%2900158-9
Temporality of body mass index, blood tests, comorbidities and medication use as early markers for pancreatic ductal adenocarcinoma (PDAC): a nested case–control study Authors: Pui San Tan , Cesar Garriga, Ashley Clift, Weiqi Liao, Martina Patone, Carol Coupland, Rachael Bashford-Rogers, Shivan Sivakumar, Julia Hippisley-Cox https://gut.bmj.com/content/gutjnl/early/2022/06/27/gutjnl-2021-326522.full.pdf
Common protocol for validation of the QCOVID algorithm across the four UK nations Authors: Steven Kerr, Chris Robertson, Vahe Nafilyan, Ronan A Lyons, Frank Kee, Christopher R Cardwell, Carol Coupland, Jane Lyons, Ben Humberstone, Julia Hippisley-Cox, Aziz Sheikh https://bmjopen.bmj.com/content/12/6/e050994.abstract?ct=
Predicting the future risk of lung cancer: development and validation of QCancer2 (10-year risk) lung model and evaluating the model performance of nine prediction models Authors: Weiqi Liao, Carol Coupland, Judith Burchardt, David Baldwin, Collaborators in the DART initiative, Fergus Gleeson, Julia Hippisley-Cox https://www.medrxiv.org/content/10.1101/2022.06.04.22275868v1
Neuropsychiatric Ramifications of Severe COVID-19 and Other Severe Acute Respiratory Infections Authors: Ashley Kieran Clift, Tom Alan Ranger, Martina Patone, Carol A. C. Coupland, Robert Hatch, Karen Thomas, Julia Hippisley-Cox, Peter Watkinson, https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2792404
Childhood, teenage and young adult cancer diagnosis during the first wave of the COVID-19 pandemic: a population-based observational cohort study in England Authors: Defne Saatci, Jason Oke, Anthony Harnden, Julia Hippisley-Cox https://adc.bmj.com/content/archdischild/early/2022/03/21/archdischild-2021-322644.full.pdf
Development and validation of clinical prediction models for breast cancer incidence and mortality: a protocol for a dual cohort study Authors: Ashley Kieran Clift, Julia Hippisley-Cox, David Dodwell, Simon Lord, Mike Brady, Stavros Petrou, Gary S. Collins https://bmjopen.bmj.com/content/12/3/e050828.abstract?ct=
Association between smoking, e-cigarette use and severe COVID-19: a cohort study Authors: Min Gao, Paul Aveyard, Nicola Lindson, Jamie Hartmann-Boyce, Peter Watkinson, Duncan Young, Carol Coupland, Ashley K Clift, David Harrison, Doug Gould, Ian D Pavord, Margaret Smith, Julia Hippisley-Cox https://academic.oup.com/ije/advance-article/doi/10.1093/ije/dyac028/6531917
Lifestyle advice for hypertension or diabetes: trend analysis from 2002 to 2017 in England Authors: John A Henry, Susan A Jebb, Paul Aveyard, Cesar Garriga, Julia Hippisley-Cox and Carmen Piernas https://bjgp.org/content/early/2022/03/07/BJGP.2021.0493
Validating the QCOVID risk prediction algorithm for risk of mortality from COVID-19 in the adult population in Wales, UK Authors: Jane Lyons, Vahé Nafilyan, Ashley Akbari, Gareth Davies, Rowena Griffiths, Ewen Harrison, Julia Hippisley-Cox, Joe Hollinghurst, Kamlesh Khunti, Laura North, Aziz Sheikh, Fatemeh Torabi, Ronan Lyons https://ijpds.org/article/view/1697/
Analysis of incidence of motor neuron disease in England 1998–2019: use of three linked datasets Authors: Judith M. Burchardt, Xue W. Mei, Tom Ranger, Christopher J. McDermott, Aleksandar Radunovic, Carol Coupland & Julia Hippisley-Cox https://www.tandfonline.com/doi/full/10.1080/21678421.2021.2016837
Development, validation, and evaluation of prediction models to identify individuals at high risk of lung cancer for screening in the English primary care population using the QResearch® database: research protocol and statistical analysis plan. Authors: Liao W, Burchardt J, Coupland C, Gleeson F, Hippisley-Cox J https://doi.org/10.1101/2022.01.07.22268789
Risk of myocarditis following sequential COVID-19 vaccinations by age and sex Authors: Martina Patone, Xue W Mei, Lahiru Handunnetthi, Sharon Dixon, Francesco Zaccardi, Manu Shankar-Hari, Peter Watkinson, Kamlesh Khunti, Anthony Harnden, Carol AC Coupland, Keith M. Channon, Nicholas L Mills, Aziz Sheikh, Julia Hippisley-Cox https://www.medrxiv.org/content/10.1101/2021.12.23.21268276v1.article-metrics
Predicting risk of pancreatic cancer in individuals with new-onset type-2 diabetes in primary care: protocol for the development and validation of a clinical prediction model (QPancreasD) Authors: Pui San Tan, Ashley Kieran Clift, Weiqi Liao, Martina Patone, Carol Coupland, Rachael Bashford-Rogers, Shivan Sivakumar, David Clifton, Stephen P Pereira, Julia Hippisley-Cox https://www.medrxiv.org/content/10.1101/2021.12.22.21268161v1
Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection Authors: Martina Patone, Xue W. Mei, Lahiru Handunnetthi, Sharon Dixon, Francesco Zaccardi, Manu Shankar-Hari, Peter Watkinson, Kamlesh Khunti, Anthony Harnden, Carol A. C. Coupland, Keith M. Channon, Nicholas L. Mills, Aziz Sheikh, Julia Hippisley-Cox https://www.qresearch.org/media/1360/s41591-021-01630-0-1-1.pdf
QCOVID in Scotland: time to recalibrate our expectations? Authors: Rishi K Gupta, Maarten van Smeden https://thorax.bmj.com/content/early/2021/11/14/thoraxjnl-2021-218169.full?ct=
External validation of the QCovid risk prediction algorithm for risk of COVID-19 hospitalisation and mortality in adults: national validation cohort study in Scotland Authors: Colin R Simpson, Chris Robertson, Steven Kerr, Ting Shi, Eleftheria Vasileiou, Emily Moore, Colin McCowan, Utkarsh Agrawal, Annemarie Docherty, Rachel Mulholland, Josie Murray, Lewis Duthie Ritchie, Jim McMenamin, Julia Hippisley-Cox, Aziz Sheikh https://thorax.bmj.com/content/early/2021/11/14/thoraxjnl-2021-217580.abstract?ct=
Neurological complications after first dose of COVID-19 vaccines and SARS-CoV-2 infection Authors: Martina Patone, Lahiru Handunnetthi, Defne Saatci, Jiafeng Pan, Srinivasa Vittal Katikireddi, Saif Razvi, David Hunt, Xue W. Mei, Sharon Dixon, Francesco Zaccardi, Kamlesh Khunti, Peter Watkinson, Carol A. C. Coupland, James Doidge, David A. Harrison, Rommel Ravanan, Aziz Sheik, Chris Robertson, Julia Hippisley-Cox https://www.nature.com/articles/s41591-021-01556-7.epdf?sharing_token=2EEiP94twaMC-qRxtlpFk9RgN0jAjWel9jnR3ZoTv0M_gNB_ZF4A8MyPfNNqp7LM5P_p2NkItT-Y5x2WPrJPNg4cFrjQq4xy3X8geR6P-Z7enVo7o2uGjuJuuDuLG6dUbzuN0z9iVZYeGdLYPJ5pBhG57HjlTy2OUDK0CmHJfOw%3D
Use of menopausal hormone therapy and risk of dementia: nested case-control studies using QResearch and CPRD databases Authors: Yana Vinogradova, Tom Dening, Julia Hippisley-Cox, Lauren Taylor, Michael Moore, Carol Coupland https://www.bmj.com/content/bmj/374/bmj.n2182.full.pdf
Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: national prospective cohort study Authors: Julia Hippisley-Cox 1, Carol Ac Coupland 2 3, Nisha Mehta 4, Ruth H Keogh 5, Karla Diaz-Ordaz 5, Kamlesh Khunti 6, Ronan A Lyons 7, Frank Kee 8, Aziz Sheikh 9, Shamim Rahman 10, Jonathan Valabhji 11, Ewen M Harrison 9, Peter Sellen 10, Nazmus Haq 10, Malcolm G Semple 11, Peter W M Johnson 12, Andrew Hayward 13, Jonathan S Nguyen-Van-Tam 3 10 https://pubmed.ncbi.nlm.nih.gov/34535466/
Identifying symptoms associated with diagnosis of pancreatic exocrine and neuroendocrine neoplasms: a nested case-control study of the UK primary care population Authors: Weiqi Liao, Ashley K Clift, Martina Patone, Carol Coupland, Arturo González-Izquierdo, Stephen P Pereira, Julia Hippisley-Cox https://pubmed.ncbi.nlm.nih.gov/34544691/
OX79 Qresearch ICNARC Covid-19 psychological outcomes Authors: Professor Peter Watkinson, Professor Julia Hippisley-Cox, Professor Kathy Rowan, Professor Carol Coupland, Dr Martina Patone, Professor David Harrison, Ms Karen Thomas, Dr Robert Hatch, Dr Pui San Tan, Dr Weiqi Liao, Dr Paul Mouncey, Dr Tom Alan Ranger, Dr Ash Kieran Clift, Mr Lukasz Cybulski https://www.qresearch.org/media/1338/ox79-qresearch-icnarc-covid-19-psychological-outcomes.pdf
Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study Authors: Julia Hippisley-Cox, Martina Patone, Xue W Mei, Defne Saatci, Sharon Dixon, Kamlesh Khunti, Francesco Zaccardi, Peter Watkinson, Manu Shankar-Hari, James Doidge, David A Harrison, Simon J Griffin, Aziz Sheikh, Carol A C Coupland https://www.bmj.com/content/374/bmj.n1931
Hormone replacement therapy and cancer survival: a longitudinal cohort study: protocol paper Authors: Tom Alan Ranger, Judith Burchardt, Ashley Kieran Clift, Winnie Xue Mei, Carol Coupland, Pui San Tan, Sharon Dixon, Christopher Robert Cardwell, Julia Hippisley-Cox https://pubmed.ncbi.nlm.nih.gov/34341043/
Sickle-cell disorders and severe COVID-19 outcomes: a cohort study Authors: Clift AK, Saatci D, Coupland CA, Dambha-Miller H, Hippisley-Cox J https://www.acpjournals.org/doi/10.7326/M21-1375
Mortality and critical care unit admission associated with the SARS-CoV-2 lineage B.1.1.7 in England: an observational cohort study Authors: Martina Patone PhD, Karen Thomas MSc, Rob Hatch BA, Pui San Tan PhD, Prof Carol Coupland PhD, Weiqi Liao PhD, Paul Mouncey MSc, Prof David Harrison PhD, Prof Kathryn Rowan PhD, Prof Peter Horby FRCP, Peter Watkinson MD, ProfJulia Hippisley-Cox FRCP https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00318-2/fulltext
Association Between Race and COVID-19 Outcomes Among 2.6 Million Children in England Authors: Defne Saatci, MD, Tom A. Ranger, PhD, Cesar Garriga, PhD, Ash Kieran Clift, MD, Francesco Zaccardi, PhD, Pui San Tan, PhD, Martina Patone, PhD, Carol Coupland, PhD, Anthony Harnden, MD, Simon J. Griffin, MD, Kamlesh Khunti, PhD, Hajira Dambha-Miller, MD, Julia Hippisley-Cox, MD https://jamanetwork.com/journals/jamapediatrics/fullarticle/2780966
External validation of a model to predict women most at risk of postpartum venous thromboembolism: Maternity clot risk Authors: Ban L, Abdul Sultan A, West J, Tata LJ, Riley RD, Nelson-Piercy C, Grainge MJ https://www.sciencedirect.com/science/article/pii/S0049384821003601?dgcid=coauthor
An external validation of the QCovid risk prediction algorithm for risk of mortality from COVID-19 in adults: a national validation cohort study in England Authors: Vahé Nafilyan, BenHumberstone, Nisha Mehta, Prof Ian Diamond, Prof Carol Coupland, Luke Lorenzi Piotr Pawelek, Ryan Schofield, Jasper Morgan, Paul Brown Prof Ronan Lyons, Prof Aziz Sheikh, Prof Julia Hippisley-Cox https://www.sciencedirect.com/science/article/pii/S2589750021000807
Associations between body-mass index and COVID-19 severity in 6·9 million people in England: a prospective, community-based, cohort study Authors: Min Gao, Carmen Piernas, Nerys M Astbury, Julia Hippisley-Cox, Stephen O'Rahilly, Paul Aveyard, Susan A Jebb https://doi.org/10.1016/S2213-8587(21)00089-9
Predicting the risk of prostate cancer in asymptomatic men: a cohort study to develop and validate a novel algorithm Authors: Hippisley-Cox J, Coupland C https://bjgp.org/content/early/2021/04/19/bjgp20X714137
Quantifying the association between ethnicity and COVID-19 mortality: a national cohort study protocol BMJ Open Authors: Hajira Dambha-Miller, Pui San Tan, Defne Saatci, Ashley Kieran Clift, Francesco Zaccardi, Carol Coupland, Patrick Locufier, Firoza Davies, Kamlesh Khunti, Simon J Griffin, Julia Hippisley-Cox https://bmjopen.bmj.com/content/11/4/e045286
Association between pre-existing respiratory disease and its treatment, and severe COVID-19: a population cohort study. The Lancet Authors: Paul Aveyard, Min Gao, Nicola Lindson, Jamie Hartmann-Boyce, Peter Watkinson, Duncan Young, Carol A C Coupland, Pui San Tan, Ashley K Clift, David Harrison, Doug W Gould, Ian D Pavord, Julia Hippisley-Cox https://www.thelancet.com/action/showPdf?pii=S2213-2600%2821%2900095-3
Association between pre-existing respiratory disease and its treatment, and severe COVID-19: a population cohort study Authors: Paul Aveyard, Min Gao, Nicola Lindson, Jamie Hartmann-Boyce, Peter Watkinson, Duncan Young, Carol A C Coupland, Pui San Tan, Ashley K Clift, David Harrison, Doug W Gould, Ian D Pavord, Julia Hippisley-Cox https://pubmed.ncbi.nlm.nih.gov/33812494/
Uptake, effectiveness, and comparative safety of new COVID-19 vaccines by age, sex, region, ethnicity, comorbidities, medication, deprivation, risk level and evidence of prior COVID infection Authors: Hippisley-Cox J, Patone M, May W, Tan PS, Watkinson P, Rowan K, Harrison H, Shankar-Hari M, Thorburn D, Khunti K, Zaccardi F, Griffin S, Callaghan C, Coupland CA. https://www.qresearch.org/media/1304/ox107_covid_vaccine_safety_protocol.pdf
Hormone replacement therapy in women with cancer and risk of cancer-specific mortality and cardiovascular disease: a protocol for a cohort study from Scotland and Wales Authors: Úna McMenamin, Blánaid Hicks, Carmel Hughes, Peter Murchie, Julia Hippisley-Cox, Tom Ranger, Carol Coupland, Chris Cardwell https://pubmed.ncbi.nlm.nih.gov/33761919/
Analysis of severe outcomes associated with the SARS-CoV-2 Variant of Concern 202012/01 in England using ICNARC Case Mix Programme and QResearch databases Authors: Martina Patone, Karen Thomas, Rob Hatch, Pui San Tan, Carol Coupland, Weiqi Liao, Paul Mouncey, David Harrison, Kathryn Rowan, Peter Horby, Peter Watkinson, Julia Hippisley-Cox https://www.medrxiv.org/content/10.1101/2021.03.11.21253364v1
The Use of Primary Care Big Data in Understanding the Pharmacoepidemiology of COVID-19: A Consensus Statement From the COVID-19 Primary Care Database Consortium Authors: Hajira Dambha-Miller, Simon J Griffin, Duncan Young, Peter Watkinson, Pui San Tan, Ashley K Clift, Rupert A Payne, Carol Coupland, Jemma C Hopewell, Jonathan Mant, Richard M Martin, Julia Hippisley-Cox https://pubmed.ncbi.nlm.nih.gov/33685875/
NHS Health Checks: Equity and outcomes 2009-17: An observational study. Authors: Garriga-Fuentes C., Robson J., Coupland C., Hippisley-Cox J. https://www.phc.ox.ac.uk/publications/1159748
Project DELTA - integrateD diagnostic solution for EarLy deTection of oesophageal cAncer: Authors: hippisley-Cox J, Fitzgerald R, Mei W, Tan PS, Coupland S, Saseini P. https://www.qresearch.org/media/1284/ox39-delta-wp1-protocol_20210211.pdf
An external validation of the QCovid risk prediction algorithm for risk of mortality from COVID-19 in adults: national validation cohort study in England (pre-print) Authors: Vahe Nafilyan, Ben Humberstone, Nisha Metha, Ian Diamond, Luke Lorenzi, Piotr Pawelek, Ryan Schofield, Jasper Morgan, Paul Brown, Ronan Lyons, Aziz Sheikh, Julia Hippisley-Cox https://www.medrxiv.org/content/10.1101/2021.01.22.21249968v1
Prostate-specific antigen testing and opportunistic prostate cancer screening: a cohort study in England, 1998–2017 Authors: Clift AK, Coupland CAC, Hippisley-Cox J https://bjgp.org/content/early/2021/01/11/bjgp20X713957
Factors influencing COVID-19 vaccine uptake among minority ethnic group Authors: Julia Hippisley-Cox https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/952716/s0979-factors-influencing-vaccine-uptake-minority-ethnic-groups.pdf
OX2 Understanding the pattern of symptoms for pancreatic neuroendocrine neoplasms (PNENs) to improve the early diagnosis of pancreatic cancer: analysis of the QResearch database Authors: Liao W, Clift A, Patone M, Coupland C, Hippisley-Cox J https://www.qresearch.org/media/1264/0x2-study-protocol-and-analysis-plan.pdf
Author's Reply to Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases Authors: Hippisley-Cox, J Ref: BMJ 2020;371:m3873 https://www.bmj.com/content/371/bmj.m3873/rr-9
NHS Health Checks for people with mental ill-health 2013–2017: an observational study Authors: Garriga C, Robson J, Coupland C, Hippisley-Cox J https://www.cambridge.org/core/journals/epidemiology-and-psychiatric-sciences/article/nhs-health-checks-for-people-with-mental-illhealth-20132017-an-observational-study/C8007A3B88ED2065148D86741904EB9C
Living risk prediction algorithm (QCOVID) for risk of hospital admission and mortality from coronavirus 19 in adults: national derivation and validation cohort study. BMJ 2020 (letter) Authors: Clift A, Semple MG, Khunti K, Coupland C, Sheikh A, Valabhji J & Hippisley-Cox J. Ref: Ref1 https://www.bmj.com/content/371/bmj.m3731/rr-4
Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people (1) Authors: Hippisley-Cox J, San Tan P, Coupland C https://heart.bmj.com/content/early/2020/11/05/heartjnl-2020-318312.full?ct=
Protocol for the development and evaluation of a tool for predicting risk of short-term adverse outcomes due to COVID-19 in the general UK population Authors: Hippisley-Cox J, Clift AC, Coupland CAC, Keogh R, Diaz-Ordaz K, Williamson E, Harrison E, Hayward A, Hemingway H, Horby P, Mehta N, Benger JK, Khunti K, Spiegelhalter D, Sheikh A, Valabhji J, Lyons RA, John Robson J, Gracie Semple M, Kee F, Johnson P, Jebb S, Tony Williams T, Coggon D https://www.medrxiv.org/content/10.1101/2020.06.28.20141986v1
Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases Authors: Yana Vinogradova, Carol Coupland, Julia Hippisley-Cox https://www.bmj.com/content/371/bmj.m3873
COVID-19 Mortality Risk in Down Syndrome: Results From a Cohort Study Of 8 Million Adults Authors: Clift AK, Coupland CAC, Keough RH, Hemingway H, Hippisley-Cox J Ref: https://doi.org/10.7326/M20-4986 https://www.acpjournals.org/doi/10.7326/M20-4986
Living risk prediction algorithm (QCOVID) for risk of hospital admission and mortality from coronavirus 19 in adults: national derivation and validation cohort study Authors: Clift AK, Coupland CAC, Keogh RH, Karla Diaz-Ordaz K, Williamson E, Harrison EM Hayward A, Harry H, Horby P, Mehta N, Benger J, Khunti K, Spiegelhalter D, Sheikh A, Valabhji J, Lyons RA, Robson J, Semple MG, Kee F, Johnson P, Jebb S, Williams T, Hippisley-Cox J Ref: 2020;371:m3731 https://doi.org/10.1136/bmj.m3731
Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people Authors: Julia Hippisley-Cox, Duncan Young, Carol Coupland, Keith M Channon, Pui San Tan, David A Harrison, Kathryn Rowan, Paul Aveyard, Ian D Pavord, Peter J Watkinson https://heart.bmj.com/content/early/2020/07/31/heartjnl-2020-317393.full
Incidence and prevalence of primary care antidepressant prescribing in children and young people in England, 1998–2017: A population-based cohort study Authors: Ruth H. Jack , Chris Hollis, Carol Coupland, Richard Morriss, Roger David Knaggs, Debbie Butler, Andrea Cipriani, Samuele Cortese, Julia Hippisley-Cox https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003215
Development and evaluation of a tool for predicting risk of short-term adverse outcomes due to COVID-19 in the general UK population; Research Protocol Authors: Julia Hippisley-Cox, Ash K. Clift, Carol Coupland, Ruth Keogh, Karla Diaz-Ordaz, Elizabeth Williamson, Ewen M. Harrison, Andrew Hayward, Harry Hemingway, Peter Horby, Nisha Mehta, Jonathan Benger, Kamlesh Khunti, David Spiegelhalter, Aziz Sheikh, Jonathan Valabhji, Ronan A. Lyons, John Robson, Calum Semple, Frank Kee, Peter Johnson, Susan Jebb, Tony Williams, David Coggon https://www.qresearch.org/media/1202/ox100-covid-19-risk-prediction-tool-112.pdf
Real-world effect of antidepressants for depressive disorder in primary care: protocol of a population based cohort study Authors: Franco De Crescenzo, Cesar Garriga, Anneka Tomlinson, Carol Coupland, Orestis Efthimiou, Seena Fazel, Julia Hippisley- Cox, Andrea Cipriani https://ebmh.bmj.com/content/early/2020/06/17/ebmental-2020-300149
Associations between COVID-19 infection, tobacco smoking and nicotine use, common respiratory conditions and inhaled corticosteroids: a prospective QResearch-Case Mix Programme data linkage study January-May 2020 Authors: Paul Aveyard, Nicola Lindson, Min Gao, Jamie Hartmann-Boyce, Margaret Smith, Duncan Young, Carol Coupland, Pui San Tan, Ashley K Clift, David Harrison, Doug W Gould, Ian Pavord, Peter Watkinson, Julia Hippisley-Cox https://www.medrxiv.org/content/10.1101/2020.06.05.20116624v1
Secondary care specialist visits made by children and young people prescribed antidepressants in primary care: a descriptive study using the QResearch database Authors: Jack, RH, Joseph, RM, Coupland, C, Butler D, Hollis, C, Morriss, Knaggs, RD, Cipriani, A, Cortese, S, Hippisley-Cox, J https://rdcu.be/b3SDJ
OX79 Coronavirus Record Linkage Project - QResearch-ICNARC COVID-19 Collaboration - RESEARCH PROGRAM PROTOCOL Authors: Professor Peter Watkinson, Professor Julia Hippisley-Cox, Professor Kathy Rowan https://www.qresearch.org/media/1193/ox79-qresearch-icnarc-covid-19-protocol-nihr-16-published.pdf
Trends in antidepressant prescriptions in children and young people in England, 1998–2017: protocol of a cohort study using linked primary care and secondary care datasets Authors: Ruth H Jack, Chris Hollis, Carol Coupland, Richard Morriss, Roger David Knaggs, Andrea Cipriani, Samuele Cortese, Julia Hippisley-Cox https://ebmh.bmj.com/content/22/3/129.long
Association of Anticholinergic Drug Exposure With Increased Occurrence of Dementia—Reply Authors: Coupland CA, Moor M, Hippisley-Cox J Ref: Association of Anticholinergic Drug Exposure With Increased Occurrence of Dementia—Authors Reply. JAMA Intern Med. 2019;179(12):1730-1731. doi:10.1001/jamainternmed.2019.4908 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2756985
Trends in antidepressant prescriptions in children and young people in England, 1998-2017: protocol of a cohort study using linked primary and secondary care datasets Authors: Jack RH, Hollis C, Coupland C, Morriss R, Knaggs RD, Cipriani A, Cortese S, Hippisley-Cox J Ref: Evidence Based Mental Health 2019 dot:10.1136/ebmental-2019-300097 https://ebmh.bmj.com/content/early/2019/06/28/ebmental-2019-300097.long
Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study Authors: Coupland CA, Hill T, Dening T, Morriss R, Moore M, Hippisley-Cox J Ref: JAMA Intern Med doi 10.1001/jamainternmed2019.0677 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2736353
Detection of familial hypercholesterolaemia: external validation of the FAMCAT clinical case-finding algorithm to identify patients in primary care Authors: Weng S, Kai J, Akyea R, Qureshi N Ref: Lancet Public Health 2019; 4; e256-64 http://www.thelancet.com/retrieve/pii/S2468266719300611
Use of hormone replacement therapy and risk of venous thromboembolism: nested case control studies using the QResearch and CPRD databases. Authors: Vinogradova Y, Coupland CA, Hippisley-Cox J. Ref: BMJ 2019; 364;k4810 https://doi.org/10.1136/bmj.k4810
Protocol to assess risk of venous thromboembolism associated with the use of hormone replacement therapy in real world settings: two nested case-control studies in primary care Authors: Vinogradova Y, Coupland CA, Hippisley-Cox J Ref: University of Nottingham ePrint http://eprints.nottingham.ac.uk/51356/
Comparison of co-morbidity and investigations for people with diabetes in Bermuda and the UK Authors: Hippisley-Cox, J Ref: QResearch report https://www.qresearch.org/media/1072/q118-bermuda-report-23-_final.pdf
Re: Use of combined oral contraceptives and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases Authors: Vinogradova Y, Coupland C, Hippisley-Cox J Ref: BMJ 2015;350:h2135 Rapid Responses https://www.bmj.com/content/350/bmj.h2135/rr-7
Risks and benefits of direct oral anticoagulants versus warfarin in a real world setting: cohort study in primary care Authors: Vinogradova Y, Coupland C, Hill T, Hippisley-Cox J Ref: BMJ 2018; 362:k2505 https://www.bmj.com/content/362/bmj.k2505.long
Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database Authors: Coupland CA, Hill T, Morriss R, Moore M, Arthur A, Hippisley-Cox J Ref: BMC Medicine 2018;16(1):36 https://doi.org/10.1186/s12916-018-1022-x
Re: Managing dyslipidaemia for the primary prevention of cardiovascular disease Authors: Hippisley-Cox J Ref: BMJ 2018;360:k946 https://www.bmj.com/content/360/bmj.k946/rr-2
Development and validation of QDiabetes-2018 risk prediction algorithm to estimate future risk of type 2 diabetes: cohort study. Authors: Hippisley-Cox J, Coupland C Ref: BMJ 2017;359 doi: 10.1136/bmj.j5019 http://www.bmj.com/content/359/bmj.j5019
Development and validation of QMortality risk prediction algorithm to estimate short term risk of death and assess frailty: cohort study Authors: Hippisley-Cox J, Coupland C Ref: BMJ 2017;358:j4208 http://bmj.com/cgi/content/full/bmj.j4208
Authors' response to letters on QRISK3 regarding the definition of severe mental illness and analysis of systolic blood pressure variability Authors: Hippisley-Cox J, Coupland C, Brindle P Ref: BMJ 2017;357:j2099 https://www.bmj.com/content/357/bmj.j2099/rapid-responses
Development and validation of risk prediction equations to estimate survival in patients with colorectal cancer: cohort study Authors: Hippisley-Cox J, Coupland C. Ref: BMJ 2017;357 doi: 10.1136/bmj.j2497 http://www.bmj.com/content/bmj/357/bmj.j2497.full.pdf
Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease: prospective cohort study Authors: Hippisley-Cox J, Coupland C, Brindle P. Ref: BMJ 2017;357 doi: 10.1136/bmj.j2099 http://www.bmj.com/content/357/bmj.j2099
Cardiovascular and neuropsychiatric risks of varenicline and bupropion in smokers with chronic obstructive pulmonary disease Authors: Kotz D, Viechtbauer W, Simpson CR, et al. Ref: Thorax 2017 doi: 10.1136/thoraxjnl-2017-210067 http://thorax.bmj.com/content/early/2017/05/04/thoraxjnl-2017-210067
Concerns on 'clinical features of bowel disease paper in patients' Authors: Hippisley-Cox J, Coupland C Ref: British Journal of General Practice 2017 http://bjgp.org/content/67/658/e336/tab-e-letters#concerns-on-clinical-features-of-bowel-disease-paper-in-patients
Incorporating cancer risk information into general practice: a qualitative study using focus groups with health professionals Authors: Hippisley-Cox J Ref: British Journal of General Practice 2017;67(657):158 http://bjgp.org/content/67/657/158.2
Diabetes treatments and risk of heart failure, cardiovascular disease and all-cause mortality: cohort study in primary care Authors: Hippisley-Cox J, Coupland CA. Ref: BMJ 2016; 354; i3477 http://www.bmj.com/content/bmj/354/bmj.i3477.full.pdf
Discontinuation and restarting in patients on statin therapy: a cohort study using a primary care database Authors: Vinogradova Y, Coupland CA, Brindle P, Hippisley-Cox J. Ref: BMJ 2016; 353:i3305. http://www.bmj.com/content/bmj/353/bmj.i3305.full.pdf
Diabetes treatments and risk of amputation, blindness, severe kidney failure, hyperglycaemia and hypoglycaemia: cohort study in primary care Authors: Hippisley-Cox J, Coupland CA Ref: BMJ 2016;352:i1450 http://www.bmj.com/content/bmj/352/bmj.i1450.full.pdf
Antidepressant use and risk of cardiovascular outcomes in people aged 20 to 64: cohort study using a primary care database Authors: Coupland CA, Hill T, Morriss R, Moore M, Arthur A, Hippisley-Cox J Ref: BMJ 2016;352:i1350 http://www.bmj.com/content/bmj/352/bmj.i1350.full.pdf
ORBIT Bleeding Risk Score and QBleed Authors: Hippisley-Cox J. Ref: European Heart Journal 2015; 09;29. http://eurheartj.oxfordjournals.org/content/early/2015/09/29/eurheartj.ehv476.explore
The NHS Health Check in England: an evaluation of the first 4 years Authors: Robson J, Dostal I, Sheikh A, Eldridge S, Madurasinghe V, Griffiths C, Coupland C, Hippisley-Cox J. Ref: BMJ Open 2016;6(1). https://bmjopen.bmj.com/content/6/1/e008840
Combined oral contraceptives and venous thromboembolism. Authors' reply to Zagarella Authors: Vinogradova Y, Coupland C, Hippisley-Cox J Ref: BMJ 2015;350:h3308 https://www.bmj.com/content/350/bmj.h3308
Concerns on “Validation of a Data Collection Tool and Stroke Risk Predictor” Authors: Hippisley-Cox J, Coupland CA, Brindle P Ref: International Journal of Stroke, 2015;10(7):E82-E82 http://journals.sagepub.com/doi/full/10.1111/ijs.12606
Antidepressant use and risk of epilepsy and seizures in people aged 20 to 64 years: cohort study using a primary care database Authors: Hill T, Coupland C, Morriss R, Moore MV, Hippisley-Cox J Ref: BMC Psychiatry 2015;15:315 http://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-015-0701-9
Sodium channel-inhibiting drugs and survival of breast, colon and prostate cancer: a population-based study Authors: Fairhurst C, Watt I, Martin F, et al. Ref: Scientific Reports 2015;5:16758. http://www.nature.com/articles/srep16758
Development and validation of risk prediction equations to estimate future risk of blindness and lower limb amputation in patients with diabetes: cohort study Authors: Hippisley-Cox J, Coupland CA. Ref: BMJ 2015;351:h5441. http://www.bmj.com/content/351/bmj.h5441
Development and validation of risk prediction equations to estimate future risk of heart failure in patients with diabetes: prospective cohort study Authors: Hippisley-Cox J, Coupland CA. Ref: BMJ Open 2015;5; 9; e008503. doi:10.1136/bmjopen-2015-008503 http://bmjopen.bmj.com/content/5/9/e008503.full
Cardiovascular and neuropsychiatric risks of varenicline: a retrospective cohort study Authors: Kotz D, Viechtbauer W, Simpson C, et al. Ref: The Lancet Respiratory Medicine 7 September 2015 http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(15)00320-3/fulltext
Use of combined oral contraceptives and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases Authors: Vinogradova Y, Coupland C, Hippisley-Cox J. Ref: BMJ 2015;350:h2135 http://www.bmj.com/content/bmj/350/bmj.h2135.full.pdf
Response to letter on statin use and risk of cataracts: firm conclusions are still off Authors: Hippisley-Cox J. Ref: Journal of Cardiovascular Pharmacology and Therapeutics 2015; doi 1177/1074248415591699 http://cpt.sagepub.com/content/early/2015/06/16/1074248415591699.extract
Development and validation of risk prediction algorithms to estimate future risk of common cancers in primary care: prospective cohort study Authors: Hippisley-Cox J Coupland CA. Ref: BMJ Open 2015; doi 10.1136/bmjopen-2015-007825 http://bmjopen.bmj.com/cgi/content/full/bmjopen-2015-007825?ijkey=c3gvpJ5FUf7lx7i&keytype=ref
Antidepressant use and risk of suicide and attempted suicide/self-harm in people aged 20 to 64: cohort study using a primary care database Authors: Coupland CA, Hill T, Morriss R, Arthur A, Moore M, Hippisley-Cox J Ref: BMJ 2015;350:h517 http://www.bmj.com/content/350/bmj.h517
Exposure to sodium channel-inhibiting drugs and cancer survival: protocol for a cohort study using the QResearch primary care database Authors: Fairhurst C, Watt I, Martin M, Bland M, Brackenbury WJ. Ref: BMJ Open 2014; 4; e006604 doi: 10.1136/bmjopen-2014-006604 http://bmjopen.bmj.com/content/4/11/e006604.full
Predicting risk of upper gastrointestinal bleed and intracranial bleeding with anticoagulants: prospective cohort study to derive and validate the QBleed score Authors: Hippisley-Cox J, Coupland CA. Ref: BMJ 2014; 349; g4606. http://www.bmj.com/content/349/bmj.g4606.full
The performance of seven QPrediction risk scores in an independent external sample of patients from general practice: a validation study Authors: Hippisley-Cox J, Coupland CA, Brindle P Ref: BMJ Open 2014;4(8):e005809 http://bmjopen.bmj.com/content/4/8/e005809.full?ijkey=XzmeoMKkPOgdBe0&keytype=ref
Validation of QRISK2-2014 in patients with diabetes Authors: Hippisley-Cox J, Coupland CA, Brindle P. https://qrisk.org/2017/QRISK2-2014-validation-in-patients-with-diabetes-1.7-web.pdf
Cardiovascular and neuropsychiatric safety of varenicline and bupropion compared with nicotine replacement therapy for smoking cessation: study protocol of a retrospective cohort study using the QResearch® general practice database Authors: Kotz D, Simpson C, Viechtbauer W, van Schayck OCP, West R, Sheikh A. Ref: BMJ Open 2014; 4; 8; e005281 doi:10.1136/bmjopen-2014-005281. http://bmjopen.bmj.com/content/4/8/e005281.full?sid=4c02ddbc-f040-4446-9545-2b1468888b05
Chickenpox and Risk of Stroke: A Self-controlled Case Series Analysis Authors: Thomas SL, Minassian C, Ganesan V, Langan SM, Smeeth L Ref: Clinical Infectious Diseases. 2014; 58(1): 61-8 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864501/
Exposure to hormonal contraceptives and risk of venous thromboembolism: a protocol for nested case-control studies using the QResearch and the CPRD databases Authors: Vinogradova Y, Coupland CA, Hippisley-Cox J. Ref: BMJ Open 2014; 44:e004499 doi:10.1136/bmjopen-2013-004499 http://bmjopen.bmj.com/content/4/4/e004499.abstract
Economic evaluation of a pharmacist-led IT-based intervention with simple feedback in reducing rates of clinically important errors in medicines management in general practices (PINCER) Authors: Elliott RA, Putman K, Franklin M, Verhaeghe, Annemans, Eden M, Hayre J, Rodgers S, Cantrill JA et al. Ref: 2013 http://www.birmingham.ac.uk/Documents/college-mds/haps/projects/cfhep/psrp/finalreports/PINCER-economics-report.pdf
Derivation and validation of QStroke score for predicting risk of ischaemic stroke in primary care and comparison with other risk scores: a prospective open cohort study Authors: Hippisley-Cox J, Coupland C, Brindle P. Ref: BMJ 2013;346 doi: 10.1136/bmj.f2573 http://www.bmj.com/content/346/bmj.f2573
Predicting risk of emergency admission to hospital using primary care data: derivation and validation of QAdmissions Authors: Hippisley-Cox J, Coupland CA. Ref: BMJ Open 2013;3:e003482 doi:10.1136/bmjopen-2013-003482. http://bmjopen.bmj.com/content/3/8/e003482.full
Exposure to bisphosphonates and risk of common non-gastrointestinal cancers: series of nested case-control studies using two primary care databases Authors: Vinogradova Y, Coupland C, Hippisley-Cox J. Ref: British Journal of Cancer; 2013; 10.1038/bjc.2013.383 http://www.nature.com/bjc/journal/v109/n3/abs/bjc2013383a.html
Safety of antidepressants in adults aged under 65: protocol for a cohort study using a large primary care database Authors: Coupland C, Morriss R, Arthur A, Moore M, Hill T, Hippisley-Cox J Ref: BMC Psychiatry 2013;13(1):135 http://www.biomedcentral.com/1471-244X/13/135
Exposure to bisphosphonates and risk of gastrointestinal cancers: series of nested case-control studies with QResearch and CPRD data Authors: Vinogradova Y, Coupland C, Hippisley-Cox J. Ref: BMJ 2013; 346:f114 http://www.bmj.com/content/346/bmj.f114
Symptoms and risk factors to identify men with suspected cancer in primary care: derivation and validation of an algorithm Authors: Hippisley-Cox J, Coupland C. Ref: British Journal of General Practice 2013; e1-e10 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529287/
Symptoms and risk factors to identify women with suspected cancer in primary care: derivation and validation of an algorithm Authors: Hippisley-Cox J, Coupland C. Ref: British Journal of General Practice 2013; e11-e21 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529288/
Bisphosphonates and gastrointestinal cancers: Authors reply to Abrahamsen and colleagues Authors: Vinogradova Y, Coupland CA, Hippisley-Cox J Ref: BMJ 2013;346:f1518 http://www.bmj.com/content/346/bmj.f1518
Validity and completeness of the NHS number in primary and secondary care: electronic data in England 1991-2013 Authors: Hippisley-Cox J Ref: University of Nottingham (2013) http://eprints.nottingham.ac.uk/3153/
QRISK2 validation by ethnic group Authors: Hippisley-Cox J, Coupland , Robson J, Brindle P Ref: Heart 2014;100(5):436. doi: 10.1136/heartjnl-2013-305355 http://heart.bmj.com/content/100/5/436
Independent external validation of QCancer (Ovarian) Authors: Hippisley-Cox J, Coupland C Ref: European Journal of Cancer Care 2013;22(4):559-560 https://doi.org/10.1111/ecc.12071
Electronic healthcare databases for active drug safety surveillance: is there enough leverage? Authors: Coloma PM, Trifirò G, Schuemie MJ, Gini R, Herings R, Hippisley-Cox J, Mazzaglia G, Picelli G, Corrao G, Pedersen L, van der Lei J, Sturkenboom M, on behalf of the EU-ADR consortium Ref: Pharmacoepidemiology and Drug Safety 2012; 21(6):611-621 http://onlinelibrary.wiley.com/doi/10.1002/pds.3197/full
Risk of stroke and oral anticoagulant use in atrial fibrillation: a cross-sectional survey Authors: Holt TA, Hunter TD, Gunnarsson C, Khan N, Cload P, Lip GYH Ref: British Journal of General Practice 2012; 62(603): pp. e710-e717(8) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459779/
Severe mental illness and cardiovascular risk. Report to West London Mental Health Trust Authors: Hippisley-Cox J Ref: Nottingham: University of Nottingham 2012
QRisk or Framingham? Authors: Robson J, Hippisley-Cox J, Coupland C Ref: British Journal of Clinical Pharmacology 2012; 74(3): 545-546 doi: 10.1111/j.1365-2125.2012.04293.x http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.2012.04293.x/abstract
Lifetime risks of cardiovascular disease in the UK Authors: Coupland C, Hippisley-Cox J, Brindle P Ref: New England Journal of Medicine 2012; 366(17): 1641-1643 https://www.nejm.org/doi/full/10.1056/NEJMc1202276
QRisk superior in diverse South Asian groups Authors: Robson J, Hippisley-Cox J, Coupland C Ref: International Journal of Clinical Practice 2012; 66(7): 722 http://onlinelibrary.wiley.com/doi/10.1111/j.1742-1241.2012.02955.x/abstract
Adding systematic family history enquiry to cardiovascular disease risk assessment: clinical utility in primary care Authors: Robson J, Hippisley-Cox J, Brindle P Ref: Annals of Internal Medicine 2012;157(2):148 http://annals.org/aim/fullarticle/1216559/adding-systematic-family-history-enquiry-cardiovascular-disease-risk-assessment-clinical
Atrial fibrillation and rheumatoid arthritis are cardiovascular risk factors Authors: Hippisley-Cox J, Coupland C, Robson J, Brindle P Ref: BMJ 2012;344:e2259 https://www.bmj.com/content/344/bmj.e2259
Derivation and validation of updated QFracture algorithm to predict risk of osteoporotic fracture in primary care in the United Kingdom: prospective open cohort study Authors: Hippisley-Cox J, Coupland C Ref: BMJ 2012;344:e3427 https://www.bmj.com/content/344/bmj.e3427
Identifying patients with suspected renal tract cancer in primary care: derivation and validation of an algorithm Authors: Hippisley-Cox J, Coupland C Ref: British Journal of General Practice 2012;62(597):e251-e260 http://bjgp.org/content/62/597/e251
Exposure to bisphosphonates and risk of cancer: a protocol for nested case–control studies using the QResearch primary care database (Protocol) Authors: Vinogradova Y, Coupland C, Hippisley-Cox J Ref: BMJ Open 2012;2(1):e000548 doi:10.1136/bmjopen-2011-000548 http://bmjopen.bmj.com/content/2/1/e000548.full
Validation of QFracture compared with FRAX. Analysis prepared for NICE 2011 Authors: Hippisley-Cox J, Coupland CA Ref: University of Nottingham, 2011 http://www.qresearch.org/PowerPointpresentations/A Validation of QFracture vs FRAX for NICE 2011 (1.3).pdf
Use of a large general practice syndromic surveillance system to monitor the progress of the influenza A (H1N1) pandemic 2009 in the UK Authors: Harcourt S, Smith G, Elliott A, Pebody R, Charlett A, Ibbotson S, Regan M, Hippisley-Cox J Ref: Epidemiology and Infection 2012;140(1):100-105 DOI: 10.1017/S095026881100046X https://www.cambridge.org/core/journals/epidemiology-and-infection/article/use-of-a-large-general-practice-syndromic-surveillance-system-to-monitor-the-progress-of-the-influenza-ah1n1-pandemic-2009-in-the-uk/72F66C5000E52D73B7D239E829EB90A8
Identifying women with suspected ovarian cancer in primary care: derivation and validation of algorithm Authors: Hippisley-Cox J, Coupland C Ref: BMJ 2012;344:d8009 http://www.bmj.com/content/344/bmj.d8009
Identifying patients with suspected pancreatic cancer in primary care: derivation and validation of an algorithm Authors: Hippisley-Cox J, Coupland C Ref: British Journal of General Practice 2012;62(594):e38-e45 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252538/
Identifying patients with suspected colorectal cancer in primary care: derivation and validation of an algorithm Authors: Hippisley-Cox J, Coupland C Ref: British Journal of General Practice 2012;62(594):e29-e37(9) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252537/
Predicting risk of bladder cancer in the UK Authors: Hippisley-Cox J, Coupland C Ref: British Journal of General Practice 2012;62(604):570–571 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481492/
Predictive effect of heartburn and indigestion and risk of upper GI malignancy Authors: Hippisley-Cox J, Coupland C Ref: British Journal of General Practice 2012;62(596):124-126 http://bjgp.org/content/62/596/124.2.long
Family History already included in QRISK which is used widely in the NHS in the UK Authors: Robson J, Hippisley-Cox J, Brindle P Ref: Annals of Internal Medicine 2012; Published 27.2.12 http://www.annals.org/content/156/4/253.abstract/reply#annintmed_el_140628
A study of the safety and harms of antidepressant drugs for older people: a cohort study using a large primary care database Authors: Coupland C, Dhiman P, Barton G, Morriss R, Arthur A, Sach T, Hippisley-Cox J Ref: Health Technology Assessment 2011;15(28):1-202 https://doi.org/10.3310/hta15280
Is low-dose aspirin use associated with a reduced risk of colorectal cancer? A QResearch primary care database analysis Authors: Logan RF, Vinogradova Y, Coupland CA, Hippisley-Cox J Ref: Gut 2011; 60(Supplement 1):A3 http://gut.bmj.com/content/60/Suppl_1/A3.1
Bayesian modeling to unmask and predict influenza A/H1N1pdm dynamics in London Authors: Birrell PJ, Ketsetzis G, Gay NJ, Cooper BS,Presanis AM, Harris RJ, Charlett A, Zhang XS, White PJ, Pebody RG, De Angelis D. Ref: Proceedings of the National Academy of Sciences of the U S A. 2011; 108(45): 18238-43. Epub 2011 Oct 31.
Combining electronic healthcare databases in Europe to allow for large-scale drug safety monitoring: the EU-ADR Project Authors: Coloma PM, Schuemie MJ, Trifiro G, Gini R, Herings R, Hippisley-Cox J, Mazzaglia G, Giaquinto C, Carrao G, Perdersen L, van der Lei J, Sturkenboom M, on behalf of the EU-ARD consortium Ref: Pharmacoepidemiology & Drug Safety 2011; 20(1): 1-11 doi 10.1002/pds.2053 http://www.qresearch.org/Public_Documents/Coloma Pharmepid Drug Saf 2011.pdf
Antidepressant use and the risk of adverse outcomes in older people: a population based cohort study Authors: Coupland C, Dhiman P, Morriss R, Arthur A, Barton G, Hippisley-Cox J Ref: BMJ 2011;343 d4551 https://www.bmj.com/content/343/bmj.d4551.long
Development and validation of risk prediction algorithm (QThrombosis) to estimate future risk of venous thromboembolism: prospective cohort study Authors: Hippisley-Cox J, Coupland C Ref: BMJ 2011;343:d4656 https://www.bmj.com/content/343/bmj.d4656
Incidence, prevalence, and trends of general practitioner-recorded diagnosis of peanut allergy in England, 2001 to 2005 Authors: Kotz D, Simpson CR, Sheikh A Ref: Journal of Allergy and Clinical Immunology 2011;127(3):623-30.e1 https://doi.org/10.1016/j.jaci.2010.11.021
Identifying patients with suspected gastro-oesophageal cancer in primary care: derivation and validation of an algorithm Authors: Hippisley-Cox J, Coupland C Ref: British Journal of General Practice 2011;61(592):e707-e714 http://bjgp.org/content/61/592/e707
Identifying patients with suspected lung cancer in primary care: derivation and validation of an algorithm Authors: Hippisley-Cox J, Coupland C Ref: British Journal of General Practice 2011;61(592):e715-e723 http://bjgp.org/content/61/592/e715
Risk of pneumonia in patients taking Statins: population-based nested case control study Authors: Vinogradova Y, Coupland C, Hippisley-Cox J Ref: British Journal of General Practice 2011; 61(592): e742-e748(7)
Exposure to Cyclooxygenase-2 Inhibitors and Risk of Cancer: Nested Case-Control Studies Authors: Vinogradova Y, Coupland C, Hippisley-Cox J. Ref: British Journal of Cancer 2011; 105(3): 452-459 doi: 10.1038/bjc.2011.252
Exposure to Cyclo-oxygenase-2 Inhibitors and risk of Cancer: nested case-control studies Authors: Vinogradova Y, Coupland C, Hippisley-Cox J. Ref: Journal of Epidemiology and Community Health 2011; 65 (Supplement 1): A44-A45 doi:10.1136/jech.2011.142976b.27 http://www.qresearch.org/Public_Documents/Vinogradova J Epid Comm Health 2011.pdf
Exposure to Statins and risk of common cancers: a series of nested case-control studies. Authors: Vinogradova Y, Coupland C, Hippisley-Cox J. Ref: BMC Cancer 2011; 11: 409: doi:10.1186/1471-2407-11-409 http://www.qresearch.org/Public_Documents/Vinogradova BMC Cancer 2011.pdf
Syndromic surveillance to assess the potential public health impact of the Icelandic volcanic ash plume across the United Kingdom, April 2010 Authors: Elliot AJ, Singh N, Loveridge P, Harcourt S, Smith S, Pnaiser R, Kavanagh K, Robertson C, Ramsay CN, McMenamin J, Kibble A, Murray V, Ibbotson S, Catchpole M, McCloskey B, Smith GE Ref: Eurosurveillance 2010;15(23):pii=19583 https://www.eurosurveillance.org/content/10.2807/ese.15.23.19583-en
Advantages of QRISK2 (2010) – the key issues is ethnicity and extent of reallocation Authors: Hippisley-Cox J, Coupland C, Robson J, Brindle P Ref: Heart 2011; 97 (6): 515 doi:10.1136/hrt.2010.221085 http://www.qresearch.org/Public_Documents/Hippisley-Cox Heart 2011.pdf
QFracture – authors response. Authors: Hippisley-Cox J, Coupland C Ref: BMJ 2011; Published 11th January 2011 http://www.bmj.com/content/339/bmj.b4229.full/reply
Early spread of the 2009 influenza A(H1N1) pandemic in the United Kingdom - use of local syndromic data, May-August 2009 Authors: Smith S, Smith GE, Olowokure B, Ibbotson S, Foord D, Maguire H, Pebody R, Charlett A, Hippisley-Cox J, Elliott AJ Ref: Eurosurveillance 2011; 16 (3): pii=19771 http://www.qresearch.org/Public_Documents/Early Spread of fH1N1 Eurosurveil Jan 11.pdf
Effects of severe mental illness on survival of people with diabetes Authors: Vinogradova Y, Coupland C, Hippisley-Cox J, Whyte S, Penny C Ref: British Journal of Psychiatry March 2010; 197: 272-277 http://www.qresearch.org/Public_Documents/Vinogradova Br J Psych 2010.pdf
Derivation, validation, and evaluation of a new QRISK model to estimate lifetime risk of cardiovascular disease: cohort study using QResearch database Authors: Hippisley-Cox J, Coupland C, Robson J, Brindle P Ref: BMJ 2010;341:c6624 https://www.bmj.com/content/341/bmj.c6624
Exposure to statins and risk of common cancers: a series of nested case-control studies Authors: Vinogradova Y, Coupland C, Hippisley-Cox J. Ref: Longitudinal and Life Course Studies 2010; 1 (3 Supplement): 254 http://www.qresearch.org/Public_Documents/Vinogradova Long Life Course Studies 2010.pdf
Antipsychotic medication and risk of thromboembolism: nested case-control study Authors: Parker C, Coupland C, Hippisley-Cox J Ref: BMJ 2010;341:c4245 https://www.bmj.com/content/341/bmj.c4245
Trends in the epidemiology of chronic obstructive pulmonary disease in England: a national study of 51 804 patients Authors: Simpson CR, Hippisley-Cox J, Sheikh A Ref: British Journal of General Practice 2010;60(576):e277-e284 http://bjgp.org/content/60/576/e277
Value of syndromic surveillance in monitoring a focal waterborne outbreak due to an unusual Cryptosporidium genotype in Northamptonshire, United Kingdom, June – July 2008 Authors: Smith S, Elliot AJ, Mallaghan C, Modha D, Hippisley-Cox J, Large S, Regan M, Smith GE Ref: Eurosurveillance 2010;15(33):pii=19643 http://www.qresearch.org/Public_Documents/Smith Euro Surv 2010.pdf
Predicting risk of Chronic Kidney Disease in men and women in England and Wales: prospective derivation and external validation of the QKidney®Scores Authors: Hippisley-Cox J, Coupland CA Ref: BMC Family Practice 2010; 11(1): 49 doi:10.1186/1471-2296-11-49 https://bmcfampract.biomedcentral.com/articles/10.1186/1471-2296-11-49
Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database Authors: Hippisley-Cox J, Coupland C. Ref: BMJ 2010; 340: c2197 (online first) http://www.qresearch.org/Public_Documents/Hippisley-Cox BMJ 2010.pdf
Individualising the risks of statins in men and women in England and Wales: population-based cohort study Authors: Hippisley-Cox J, Coupland C Ref: Heart 2010; 96: 939-947 http://www.qresearch.org/Public_Documents/JHC Heart 2010.pdf
Trends in the epidemiology of smoking recorded in UK general practice Authors: Simpson CR, Hippisley-Cox J, Sheikh A Ref: British Journal of General Practice 2010;60:e121-e127 http://bjgp.org/content/60/572/e121
Diagnostic precision of Primary Care electronic database for study of gastrointestinal bleeding and its ability to detect the influence of aspirin Authors: Leighton M, Vinogradova Y, Shonde A, Atherton JC, Logan RF, Avery A, Kendrick D, Hippisley-Cox J, Hawkey CJ Ref: Gastroenterology 2009; 136, (Issue 5, Supplement 1), A-612 (Abstract T1973) http://www.qresearch.org/Public_Documents/Leighton Gastro 2009.pdf
Increased Aspirin Use and Upper Gastrointestinal Bleeding Rates in Socially Deprived Patients Authors: Vinogradova Y, Leighton M, Avery A, Logan RF, Kendrick D, Atherton JC, Shonde A, Hippisley-Cox J, Hawkey CJ Ref: Gastroenterology 2009; 136 (5, Supplement 1): A-69 (Abstract 408) http://www.qresearch.org/Public_Documents/Vinogradova Gastro 2009.pdf
Data mining on electronic health record databases for signal detection in pharmacovigilance: which events to monitor? Authors: Trifirò G, Pariente A, Coloma PM, Kors JA, Polimeni G, Miremont-Salamé G, Catania MA, Salvo F, David A, Moore N, Caputi AP, Sturkenboom M, Molokhia M, Hippisley-Cox J, DiazC, van der Lei J, Fourrier-Reglat A on behalf of the EU-ADR group Ref: Pharmacoepidemiology & Drug Safety 2009; 18 (12): 1176-1184 http://www.qresearch.org/Public_Documents/Trifiro Pharmacoepid Drug Saf 2009.pdf
A semantic approach for the homogenous identification of events in eight patient databases: a contribution to the European ALERT Project. Authors: Avillach P, Mougin Fa, Jouber Mb, Thiessard F, Pariente A, Dufour J, Trifirò G, Polimeni G, Catania GA, Carlo Giaquintoe, Mazzaglia G, Baio G, Herings R, Gini R, Hippisley-Cox J, Molokhia M, Pedersen L, Fourrier-Réglat A, Sturkenboom M, Fieschi M. Ref: Studies in Health Technology and Informatics 2009; 150: 190-194
Predicting risk of osteoporotic fracture in men and women in England and Wales: prospective derivation and validation of QFracture Scores Authors: Hippisley-Cox J, Coupland C Ref: BMJ 2009:339:b4229 https://www.bmj.com/content/339/bmj.b4229
Predicting risk of type 2 diabetes in England and Wales: prospective derivation and validation of the QDScore Authors: Hippisley-Cox J, Coupland C, Robson J, Sheikh A, Brindle P Ref: BMJ 2009;338:b880 https://www.bmj.com/content/338/bmj.b880
Co-morbidity, healthcare utilisation and process of care measures in patients with congenital heart disease in the UK: cross-sectional, population-based study with case–control analysis Authors: Billet J, Cowie M, Gatzoulis MA, Voner Muhl IF, A Majeed. Ref: Heart 2008; 94: 1194-1199 doi:10.1136/hrt.2007.122671 http://www.qresearch.org/Public_Documents/Billet Heart 2008.pdf
Identification of new risk factors for pneumonia: population-based case-control study Authors: Vinogradova Y, Hippisley-Cox J, Coupland C Ref: British Journal of General Practice 2009;59(567):e329-e338 http://bjgp.org/content/59/567/e329
Health Inequalities in Primary Care: Effect of Spearhead Primary care Trusts 2002-2009 Authors: Hippisley-Cox J Ref: University of Nottingham, October 2009
Transmitted Infections in General Practice: Analysis using QRESEARCH database 2002-2006 Authors: Joint Collaboration of the Health Protection Agency and QRESEARCH Ref: 2009
Trends in consultation rates in General Practice 1995/1996 to 2008/2009: Analysis of the QResearch® database. Final Report to the NHS Information Centre and Department of Health. Authors: Hippisley-Cox J, Vinogradova Y Ref: Published by The NHS Information Centre for Health and Social Care, part of the Government Statistical Service. September 2009. ISBN 978-1-84636-328-3
Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2 Authors: Hippisley-Cox J, Coupland C, Vinogradova Y, Robson J, Minhas R, Sheikh A, Brindle P Ref: BMJ 2008;336:1475-1482 https://www.bmj.com/content/336/7659/1475
Trends in the epidemiology and prescribing for eczema in England. Authors: Simpson C, Newton J, Hippisley-Cox J, Sheikh A Ref: Journal of the Royal Society of Medicine 2009; 102; 108-117 http://www.qresearch.org/Public_Documents/Simpson J R Soc Med 2009.pdf
Incidence of oronasal haemorrhage in infancy presenting to general practice in the UK Authors: McIntosh N, Chalmers J Ref: British Journal British General Practice 2008;58(557):877-879 http://bjgp.org/content/58/557/877
Trends in the epidemiology and prescribing of mediciation for allergic rhinitis in England Authors: Ghouri N, Hippisley-Cox J, Newton J, Sheikh A. Ref: Journal of the Royal Society of Medicine 2008; 101; 466-472 http://www.qresearch.org/Public_Documents/Trends in the epidemiology and prescribing of medication for allergic rhinits in England.pdf
Incidence and prevalence of multiple allergic disorders recorded in a national primary care database Authors: Simpson C, Newton J, Hippisley-Cox J, Sheikh A Ref: Journal of the Royal Society of Medicine 2008;101; 558-563 http://www.qresearch.org/Public_Documents/Simpson J R Soc Med 2008.pdf
What is the Optimum Model of Service Delivery for Transient Ischaemic Attack? Authors: Mant J, Ryan R, McManus R, Fletcher K, Kandiyali R, Barton P, Bryan S, Stevens A, Ford G, Rotherwell P Ref: Report for the National Co-ordinating Centre for NHS Service Delivery and Organisation R&D (NCCSDO), April 2008 https://eprints.soton.ac.uk/369987/1/FR-08-1504-112.pdf
Trends in national incidence, lifetime prevalence and adrenaline prescribing for anaphylaxis in England Authors: Simpson C, Hippisley-Cox J, Sheikh A Ref: Journal of the Royal Society of Medicine 2008;101; 139-143 http://www.qresearch.org/Public_Documents/Simpson JRSM 2008.pdf
Identifying undiagnosed diabetes: cross-sectional survey of 3.6 million patients’ electronic records Authors: Holt TA, Stables D, Hippisley-Cox J, O’Hanlon S, Majeed A Ref: British Journal of General Practice 2008;58(548);192-196 http://bjgp.org/content/58/548/192
Performance of the QRISK cardiovascular risk prediction algorithm in an independent UK sample of patients from general practice: a validation study Authors: Hippisley-Cox J, Coupland C, Vinogradova Y, Robson J, Brindle P Ref: Heart 2008;94:34-39 http://heart.bmj.com/content/94/1/34.long
Uptake of pneumococcal polysaccharide vaccine in at-risk populations in England and Wales, 1999-2005 Authors: Pebody R, Hippisley-Cox J, Pringle M, Painter M, Charlett A, Smith GE Ref: Epidemiology & Infection 2008; 136: 360-369 doi:10.1017/S0950268807008436 http://www.qresearch.org/Public_Documents/Epi Infect 2008 uptake of pneumococcal.pdf
Clinical Care and Delivery Quality of diabetes care in patients with schizophrenia and bipolar disorder: cross-sectional study Authors: Whyte S, Penny C, Phelan M, Hippisley-Cox J, Majeed A
Electronic Health Indicator Data (eHID) Authors: Fleming D, Elliott C, Pringle M, Anderson J, Hebbrecht G, Nardi R, et al. Ref: Report to the European Commission. Birmingham: Royal College of General Practitioners, 2008
Sexual Health in the South East Authors: : A collaborative report by the Health Protection Agency South East and the South East Public Health Observatory. 2008
Primary Care Surveillance in the UK: Action, Outcomes, Benefits. Authors: Cooper DL, Smith GE, Elliott D, Harcourt S, Loveridge P, Smith S, Ibbotson S, George R, Hippisley-Cox J Ref: Oral presentation. Advances in Disease Surveillance 2007; 2: 100 http://www.qresearch.org/Public_Documents/Cooper Adv in Dis Surv 2007.pdf
Quality of diabetes care in patients with severe mental illness: cross-sectional study Authors: Whyte S, Penny C, Phelan M, Hippisley-Cox J, Majeed A Ref: Diabetic Medicine 2007; 22: 1442-1448 http://www.qresearch.org/Public_Documents/Whyte Diabetes Med 2007.pdf
Measuring performance and missing the point? Authors: Heath I, Hippisley-Cox J Smeeth L. Ref: BMJ 2007;335:1075-1076 https://www.bmj.com/content/335/7629/1075
Risk of malignancy in patients with schizophrenia or bipolar disorder: nested case control study Authors: Hippisley-Cox J, Vinogradova Y, Coupland C, Parker C Ref: Archives of General Psychiatry 2007; 64; 1368-1376 http://www.qresearch.org/Public_Documents/Risk of Malignancy in Patients With Schizophrenia.pdf
Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: prospective open cohort study Authors: Hippisley-Cox J, Coupland C, Vinogradova Y, Robson J, May M, Brindle P Ref: BMJ 2007; 335:136-141 https://www.bmj.com/content/335/7611/136
Risk of colorectal cancer in patients taking statins and non-steroidal anti-inflammatory medication: nested case control study Authors: Vinogradova Y, Hippisley-Cox J, Coupland C, Logan R Ref: Gastroenterology 2007; 133; 393-402 http://www.qresearch.org/Public_Documents/Statins and colorectal cancer Gastroenterology 2007.pdf
Inequalities in uptake of influenza vaccine by deprivation and risk group: time trends analysis Authors: Coupland C, Harcourt SE, Vinogradova Y, Smith GE, Joseph CA, Pringle M, Hippisley-Cox J Ref: Vaccine 2007; 25 (42): 7363-7371 http://www.qresearch.org/Public_Documents/Coupland Vaccine 2007.pdf
Inequalities in uptake of influenza vaccine by deprivation and risk group: time trends analysis (1) Authors: Coupland CAC, Harcourt S, Vinogradova Y, Smith G, Joseph C, Pringle M, Hippisley-Cox J. Ref: Journal of Epidemiology & Community Health 2007; 61 (Suppl 1): A40 http://www.qresearch.org/Public_Documents/Inequalities in uptake of influenza vaccine by deprivation.pdf
Rectal and postmenopausal bleeding: consultation and referral of patients with and without severe mental health problems Authors: Parker C, Hippisley-Cox J, Coupland C, Vinogradova Y Ref: British Journal of General Practice 2007;57(538):371-376 http://bjgp.org/content/57/538/371
Inequalities in the identification and treatment of hyperlipidaemia in coronary heart disease in patients with serious mental health problems: cross-sectional study Authors: Hippisley-Cox J, Parker C, Coupland C, Vinogradova Y Ref: Heart 2007; 93: 1256-1262 doi:10.1136/hrt.2006.110171 http://www.qresearch.org/Public_Documents/Inequalities in the primary care of patients with coronary heart disease and serious mental health problems.pdf
Developing a national primary care based early warning system for Health Protection – a surveillance tool for the future? Analysis of routinely collected data. Authors: Smith GE, Hippisley-Cox J, Harcourt SE, Heaps M, Painter M, Porter, A, Pringle M Ref: Journal of Public Health Medicine 2007; 29 (1) :75–82 http://www.qresearch.org/Public_Documents/Developing a national primary care-based early warning.pdf
Primary Care Surveillance in the UK: Actions, Outcomes, Benefits Authors: Cooper DL, Smith GE, Elliot D, Harcourt S, Loveridge P, Smith S, Ibbotson S, George R. Hippisley-Cox J Ref: Advances in Disease Surveillance 2007; 2: 100 http://www.qresearch.org/Public_Documents/Primary Care Surveillance in the UK %E2%80%93 Actions, Outcomes, Benefits.PDF
A description of the 4th version of the QRESEARCH database. Report to the Department of Health, 2007 Authors: QResearch Ref: http://www.qresearch.org/Public_Documents/DataValidation/A description of the 4th version of the QRESEARCH database.pdf
An analysis of the top ten most commonly prescribed chemical entities in QRESEARCH. Report to the Department of Health, 2007 Authors: QRESEARCH http://www.qresearch.org/Public_Documents/DataValidation/An analysis of the top ten most commonly prescribed chemical entities in QRESEARCH.pdf
A report on basic prescribing rates in older people using QRESEARCH. Report to the Department of Health, 2007. Authors: QRESEARCH
Comorbidity of diseases in the new GMS contract for GPs: analysis of QRESEARCH data Authors: Hippisley-Cox J, Pringle M. Ref: Report to the Department of Health, 2007 http://www.qresearch.org/Public_Documents/DataValidation/Co-morbidity of diseases in the new GMS contract for GPs.pdf
Comparison of recording of procedures between QRESEARCH and Hospital Episode Statistics Authors: Hippisley-Cox J, Ryan R, Pringle M Ref: Report to the Department of Health, 2007 http://www.qresearch.org/Public_Documents/DataValidation/An analysis of prescribing of methylphenidate hydrochloride.pdf
Delivery and Organisation R&D (NCCSDO): NCCSDO Authors: Mant J, Barton P, Ryan R, McManus R, Fletcher K, Kandiyali R, et al.
Determinants of consultation rates over time: Implications for estimating the national volume of consultations Authors: Fenty J, Coupland C, Hippisley-Cox J, Gravelle H Ref: QRESEARCH research highlights. Leeds: The Information Centre, 2007:79
Diabetes in the UK: analysis of QRESEARCH data. Report to the Department of Health, 2007 Authors: QRESEARCH Ref: http://www.qresearch.org/Public_Documents/DataValidation/Diabetes in the UK analysis of QRESEARCH data.pdf
Distribution of risk factors and cardiovascular risk in QRESEARCH in 2007. Report to the Department of Health Authors: Hippisley-Cox J Ref: December 2007 http://www.qresearch.org/Public_Documents/JHC cardiovascular risk report 2007.pdf
Evaluation of standards of care for osteoporosis and falls in primary care. Authors: Hippisley-Cox J, Bayly J, Potter J, Fenty J, Parker C Ref: QRESEARCH research highlights. Leeds: The Information Centre, 2007:97 http://www.qresearch.org/Public_Documents/Evaluation of standards of care for osteopoorosus and falls in primary care.pdf
Obesity in the UK: analysis of QRESEARCH data. Report to the Department of Health, 2007 Authors: QRESEARCH Ref: http://www.qresearch.org/Public_Documents/DataValidation/Obesity in the UK.pdf
Patterns of prescribing of selective serotonin reuptake inhibitors in children in QRESEARCH Authors: QRESEARCH Ref: Report to the Department of Health, 2007 http://www.qresearch.org/Public_Documents/DataValidation/Patterns of prescribing of selective serotonin reputake inhibitors in children.pdf
Polypharmacy in the elderly: an analysis of QRESEARCH data Authors: QRESEARCH Ref: Report to the Department of Health, 2007 http://www.qresearch.org/Public_Documents/DataValidation/Polypharmacy in the elderly.pdf
Primary care epidemiology of allergic disorders: analysis using QRESEARCH database 2001-2006 Authors: Hippisley-Cox J, Jumbu G, Fenty J, Holland R, A. P, Heaps M. Ref: QRESEARCH research highlights. Leeds: The Information Centre, 2007:84. http://www.qresearch.org/Public_Documents/HSCIC allergies report from QRESEARCH .pdf
Repeat prescribing in the elderly: an analysis of QRESEARCH data Authors: QRESEARCH Ref: Report to the Department of Health, 2007 http://www.qresearch.org/Public_Documents/DataValidation/Prescribing in older people by BNF chapter.pdf
Report to the National Audit Office: Quality of care for Stroke and TIA in General Practice using the new GMS contract indicators Authors: QRESEARCH http://www.qresearch.org/Public_Documents/NAO_Stroke_GMS_GP_activity.pdf
Revising the General Medical Services Formula Authors: Hippisley-Cox J, Coupland C, Pringle M, Marshall A, Ford J Ref: Report to the Information Centre, 2007
QRESEARCH data. Report to the Department of Health, 2007 Authors: QRESEARCH http://www.qresearch.org/Public_Documents/DataValidation/Trends and variations in GMS indicators for diabetes.pdf
Quality and Outcomes Time Series Analysis in QRESEARCH 2001 to 2006. Authors: Hippisley-Cox J, Vinogradova Y, Coupland C, Heaps M Ref: QRESEARCH research highlights. Leeds: The Information Centre, 2007:39
The population prevalence and inter-practice variation of diabetes: analysis of QRESEARCH data. Authors: QRESEARCH Ref: Report to the Department of Health, 2007 http://www.qresearch.org/Public_Documents/DataValidation/The population prevalence and inter-practice variation of diabetes.pdf
Trends and variations in GMS indicators for coronary heart disease: analysis of QRESEARCH data Authors: QRESEARCH Ref: Report to the Department of Health, 2007 http://www.qresearch.org/Public_Documents/DataValidation/Trends and variations in GMS quality indicators for coronary heart disease.pdf
Trends and variations in GMS indicators for diabetes: analysis of QResearch data Authors: QResearch Ref: Report to the Department of Health, 2007
Trends and variations in GMS indicators for hypertension: analysis of QResearch data. Authors: QResearch Ref: Report to the Department of Health 2007
Trends in Consultation Rates in General Practice 1995 to 2006: Analysis of the QRESEARCH database Authors: Hippisley-Cox J, Fenty J, Heaps M Ref: QRESEARCH research highlights. Leeds: The Information Centre, 2007:29 http://www.qresearch.org/Public_Documents/Trends in consultation rates in general practice 1995 to 2006.pdf
Types of clinical and administrative user in QRESEARCH Authors: QRESEARCH Ref: Report to the Department of Health, 2007 http://www.qresearch.org/Public_Documents/DataValidation/Types of clinical and administrative users in QRESEARCH.pdf
Validation of QFLU – comparison of key indicators with the RCGP weekly returns service 2003-2006 Authors: Hippisley-Cox J, Fenty J, Fleming D, Elliott A, Porter A Ref: Report to the Health Protection Agency, 2007
Diabetes in the United Kingdom: Analysis of QRESEARCH data Authors: QRESEARCH Ref: Report to the Department of Health, 2007 http://www.qresearch.org/Public_Documents/DataValidation/Diabetes in the UK analysis of QRESEARCH data.pdf
Risk of malignancy in patients with mental health problems (abstract). Authors: Vinogradova Y, Hippisley-Cox J, Coupland C, Parker C Ref: Family Practice 2006; 23: 1-142 Supplement
The effect of statins on mortality in patients with ischaemic heart disease: population-based cohort study with case control analysis. Authors: Hippisley-Cox J, Coupland CAC Ref: Heart 2006; 92; 752-758 http://www.qresearch.org/Public_Documents/Reprints/Others/Statins paper in heart 2006.pdf
Sex inequalities in access to care for patients with diabetes in primary care: questionnaire survey Authors: Hippisley-Cox J, Yates J, Pringle M, Coupland C, Hammersley V Ref: British Journal of General Practice 2006;56(526):342-348 http://bjgp.org/content/56/526/342
QFLU: new influenza monitoring in UK primary care to support pandemic influenza planning Authors: Hippisley-Cox J, Smith S, Smith G, Porter A, Heaps M, Holland R, Fenty J, Harcourt S, George R, Charlett A, Pebody R, Painter M Ref: Euro Surveillance 2006 Jun 22;11(6):E060622.4 http://www.eurosurveillance.org/ew/2006/060622.asp
Determinants of consultation rates over time: implications for estimating the national volume of consultations. Authors: Fenty J, Coupland C, Hippisley-Cox J, Gravelle H Ref: Report to the Health and Social Care Information Centre, 2006
Factors associated with variations in consultation rates. Authors: Fenty J, Coupland C, Hippisley-Cox J Ref: Report to the NHS Information Centre, April 2006
Health outcomes for patients with serious mental health problems. Authors: Hippisley-Cox J, Parker C, Vinogradova Y, Coupland C Ref: Second report to the Disability Rights Commission, February 2006
Primary care epidemiology of allergic disorders: analysis using QRESEARCH database 2001-2006 (1) Authors: Hippisley-Cox J, Jumbu G,Fenty J, Holland R, Porter A, Heaps M Ref: Report to the Health and Social Care Information Centre, 2006
Quality of care and health outcomes for patients with serious mental health problems Authors: Hippisley-Cox J, Parker C, Vinogradova Y, Coupland C. Ref: Report to the Disability Rights Commission, 2006
Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis Authors: Hippisley-Cox J, Coupland C Ref: BMJ 2005;330:1366-1374 https://www.bmj.com/content/330/7504/1366
Effect of combinations of drugs on all cause mortality in patients with ischaemic heart disease: nested case control analysis Authors: Hippisley-Cox J, Coupland C Ref: BMJ 2005;330:1059-1063 https://www.bmj.com/content/330/7499/1059
Risk of adverse gastrointestinal outcomes in patients taking cyclo-oxygenase-2 or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis Authors: Hippisley-Cox J, Coupland C, Logan R Ref: BMJ 2005;331:1310-1316 https://www.bmj.com/content/331/7528/1310
Coronary heart disease prevention and age inequalities: the first year of the National Service Framework for CHD Authors: Hippisley-Cox J, Pringle M, Cater R, Coupland C, Meal A Ref: British Journal of General Practice 2005;55(514):369-375 http://bjgp.org/content/55/514/369.long
Assessing the accuracy of a computerised decision support system for digoxin dosing in primary care: an observational study Authors: Kroese, WLG, Avery AJ, Savelyich BSP, Brown NS, Schers H, Howard R, Hippisley-Cox J, Horsfield P. Ref: Clinical Pharmacology & Therapeutics 2005; 30: 279-283 http://www.qresearch.org/Public_Documents/Kroese Clin Pharm Therap 2005.pdf
Smoking cessation treatments within primary care. Prospective cohort study Authors: Wilson A, Hippisley-Cox J, Coupland C, Coleman T, Britton J, Barratt S Ref: Tobacco Control 2005;14:242-246 http://tobaccocontrol.bmj.com/content/14/4/242.long
Comparison of key practice characteristics between general practices in England and Wales and general practices in the QRESEARCH database Authors: Hippisley-Cox J, Vinogradova Y, Coupland, C, Pringle M Ref: Report to the Information Centre, 2005 http://www.qresearch.org/Public_Documents/Characteristics of QRESEARCH practices _database version 8_ v1.0.pdf
Health Inequalities Experienced By People With Schizophrenia And Manic Depression: Analysis Of General Practice Data In England And Wales Authors: Hippisley-Cox J, Pringle M Ref: Final report to the Disability Rights Commission April 2005 http://www.qresearch.org/Public_Documents/Qresearch DRC Final Report April 2005.pdf
Quality of care for stroke and TIA in general practice using the new GMS contract indicators Authors: Hippisley-Cox J, Fenty J, Langford G, Pringle M, Coupland C Ref: Report to the National Audit Office, November 2005
Results of the pairwise analysis for trends in consultation rates in UK general practices the calendar years 1995 to 2004 Authors: Hippisley-Cox J, Fenty J, Heaps M, Pringle M Ref: Report to the Information Centre, November 2005
Revising the GMS formula allocation formula Authors: Hippisley-Cox J, Coupland C, Pringle M, Marshall A, Ford J Ref: Report to the NHS Information Centre, 2005
Trends in consultation rates in UK general practices the calendar years 1995 to 2004 Authors: Hippisley-Cox J, Fenty J, Heaps M, Pringle M Ref: Report to the Information Centre, November 2005
QRESEARCH: a new general practice database for research Authors: Hippisley-Cox J, Stables D, Pringle M Ref: Journal of Informatics in Primary Care 2004; 12; 49-50.
Identifying patients with medication errors using the QRESEARCH database Authors: Avery A, Hippisley-Cox J, Ryan R, Armstrong S, Morris C, Cantrill J Ref: Pharmacoepidemiology and Drug Safety 2004; 13 (Supplement l): S61-62
Association of deprivation, ethnicity and sex with quality indicators for diabetes: population based survey of 53,000 patients in primary care Authors: Hippisley-Cox J, O’Hanlon S, Coupland C Ref: BMJ 2004;329:1267-1269 https://www.bmj.com/content/329/7477/1267
Prevalence, care and outcomes for patients with diet controlled diabetes in primary care: cross sectional survey Authors: Hippisley-Cox J, Pringle M Ref: Lancet 2004; 364: 423-442 http://www.qresearch.org/Public_Documents/Hippisley-Cox Lancet 2004.pdf
Primary and secondary prevention, and age inequalities: the effect of the first year of the implementation of the National Service Framework for Coronary Heart Disease in general practices in Trent: follow-up study Authors: Hippisley-Cox J, Pringle M, Coupland C, Cater R, Meal A Ref: British Journal of General Practice 2004; 12: 179-184
Achievement of new General Medical Services Indicators for Diabetes Authors: Hippisley-Cox J, Pringle M Ref: Report to the Department of Health, 2004
An analysis of prescribing of Methylphenidate Hydrochloride in QRESEARCH Authors: QRESEARCH Ref: Report to the Department of Health, 2004
An analysis of prescribing of SSRIs to Children Authors: Hippisley-Cox J, Pringle M, Ryan R. Ref: Report to the Statistics Division, Department of Health, 2004
An assessment of basic data quality in the pilot QRESEARCH database Authors: Hippisley-Cox J, Pringle M, Ryan R Ref: Report to the Statistics Division, Department of Health, 2004
Basic prescribing rates in older people Authors: Hippisley-Cox J, Pringle M, Ryan R Ref: Report to the Statistics Division, Department of Health, 2004
Comparison of the recording of procedures on QRESEARCH and HES Authors: Hippisley-Cox J, Pringle M, Ryan R Ref: Report to the Statistics Division, Department of Health, 2004
Comparing the top ten chemical entities in PACT and QRESEARCH Authors: Hippisley-Cox J, Pringle M, Ryan R. Ref: Report to the Statistics Division, Department of Health, 2004
Defining user types in QRESEARCH Authors: Hippisley-Cox J Ref: Report to the Statistics Division, Department of Health, 2004
Description of the National Database (4th download) Authors: Hippisley-Cox J Ref: Report to the Department of Health, 2004
Diabetes in the UK, 1994 to 2003 Authors: Hippisley-Cox, J. Ryan R Ref: Report to the Department of Health, 2004
Incidence, prevalence and care of patients with stroke in primary care in 2004 Authors: Hippisley-Cox J, Pringle M, Ryan R Ref: Report to the National Stroke Audit team, 2004
Incidence, prevalence and mortality of diabetes in the UK 1994 to 2003 Authors: Hippisley-Cox J, Ryan R Ref: Report to the Statistics Division, Department of Health, 2004
Inter-practice variation in the prevalence of diabetes Authors: Hippisley-Cox J Ref: Report to the Department of Health, 2004
First National Stroke Audit in Primary Care Authors: QRESEARCH Ref: Final Report to the National Audit Office, 2004 http://www.qresearch.org/Public_Documents/National_Stroke_Audit_Final_Report_2004.pdf
Morbidity and mortality on the QRESEARCH database Authors: Hippisley-Cox J, Pringle M, Ryan R Ref: Report to the Statistics Division, Department of Health, 2004
Polypharmacy in the elderly Authors: Hippisley-Cox J, Pringle M, Ryan R Ref: Report to the Statistics Division, Department of Health, 2004
Prescribing in older people by BNF Chapter Authors: Hippisley-Cox J, Pringle M Ref: Report to the Statistics Division, Department of Health, 2004
Prescribing of Methylphenidate Hydrochloride in children Authors: Hippisley-Cox J, Pringle M, Ryan R Ref: Report to the Statistics Division, Department of Health, 2004
Prevalence of conditions in the new General Medical Services Authors: Hippisley-Cox J, Pringle M Ref: Report to the Department of Health, 2004
Stroke: prevalence, incidence & care in general practice 2002-2004 Authors: Hippisley-Cox J, Pringle M, Ryan R. Ref: Final Report to the National Stroke Audit Team, Royal College of Physicians, September 2004
The effect of age, sex, deprivation and other factors on electrolytes in patients on ACE inhibitors or loop diuretics in primary care: a case control study Authors: Nwabuoku MPH Ref: Thesis. University of Nottingham 2004
Trends in obesity in the UK 1994 to 2003 Authors: Hippisley-Cox J. Ryan R Ref: Report to the Department of Health, 2004
Understanding QRESEARCH data structures Authors: Hippisley-Cox J Ref: Report to the Statistics Division, Department of Health, 2004

›

Research Papers

Development and evaluation of clinical prediction models for risk-stratified early detection, prevention and management of breast cancer

A protocol to assess antipsychotics prescribing and physical health monitoring in children and young people: a cohort study using primary care data from QResearch

Identifying early symptoms associated with a diagnosis of childhood, adolescent and young adult cancers: a population-based nested case-control study

Hormone replacement therapy and cancer mortality in women with 17 site-specific cancers: a cohort study using linked medical records

Incidence of menstrual symptoms suggestive of possible endometriosis in adolescents: and variance in these by ethnicity and socio-economic status

How did the COVID-19 pandemic affect cancer patients in England who had hospital appointments cancelled?

Uptake, efectiveness and safety of COVID-19 vaccines in individuals at clinical risk due to immunosuppressive drug therapy or transplantation procedures: a population-based cohort study in England

Associations between BMI and hospital resource use in patients hospitalised for COVID-19 in England: a community-based cohort study

QCOVID Risk Prediction Tool Final Report to NIHR Policy Research Programme

Safety outcomes following COVID-19 vaccination and infection in 5.1 million children in England

Effectiveness and safety of COVID-19 vaccination in people with blood cancer

Predicting the risk of pancreatic cancer in adults with new-onset diabetes: development and internal–external validation of a clinical risk prediction model

Development and validation of a new algorithm for improved cardiovascular risk prediction

Mortality and adverse events associated with statin use in primary care patients with depression: a real-world, population-based cohort study

Exploring the interface between adolescent dysmenorrhoea and endometriosis: a protocol for a cohort and nested case-control study within the QResearch Database

Importance of accurate and accessible recording of healthcare contacts in mental health

Impact of vaccination on COVID-19-associated admissions to critical care in England: a study of population linked data with quantitative bias analysis for linkage error.

Analysis of primary care electronic health record data of people living with hepatitis B virus: infection and hepatocellular carcinoma risk associated with socio-economic deprivation

Dynamic updating of clinical survival prediction models in a changing environment

Ethical and legal implications of implementing risk algorithms for early detection and screening for oesophageal cancer, now and in the future

Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data

Uptake, effectiveness and safety of COVID-19 vaccines in the immunocompromised population: A population-based cohort study in England

Development and validation of a novel risk prediction algorithm to estimate 10-year risk of oesophageal cancer in primary care: prospective cohort study and evaluation of performance against two other risk prediction models

Predicting 10-year breast cancer mortality risk in the general female population in England: a model development and validation study

Risk prediction of covid-19 related death or hospital admission in adults testing positive for SARS-CoV-2 infection during the omicron wave in England (QCOVID4): cohort study

An external validation of the QCOVID3 risk prediction algorithm for risk of hospitalisation and death from COVID-19: An observational, prospective cohort study of 1.66m vaccinated adults in Wales, UK

Disparities in care and outcomes for primary liver cancer in England during 2008–2018: a cohort study of 8.52 million primary care population using the QResearch database

The current status of risk-stratified breast screening

Development and internal-external validation of statistical and machine learning models for breast cancer prognostication: cohort study

Predicting the future risk of lung cancer: development, and internal and external validation of the CanPredict (lung) model in 19·67 million people and evaluation of model performance against seven other risk prediction models

Uptake of COVID-19 vaccination in people with blood cancer: Population-level cohort study of 12 million patients in England

Factors influencing influenza, pneumococcal and shingles vaccine uptake and refusal in older adults: a population-based cross-sectional study in England

Estimating the epidemiology of chronic Hepatitis B Virus (HBV) infection in the UK: what do we know and what are we missing?

Ethnic disparities in COVID-19 outcomes: a multinational cohort study of 20 million individuals from England and Canada

Analysis of uptake, effectiveness and safety of COVID-19 vaccinations in pregnancy using the QResearch database: research protocol and statistical analysis plan

QFracture 2016 Annual Update Information

Preexisting Neuropsychiatric Conditions and Associated Risk of Severe COVID-19 Infection and Other Acute Respiratory Infections

Uptake of COVID-19 Vaccination in People with Haematological Malignancy and Other High-Risk Blood Disorders: Cohort Analysis of 12 Million Patients in England

Development and validation of personalised risk prediction models for early detection and diagnosis of primary liver cancer among the English primary care population using the QResearch® database: research protocol and statistical analysis plan

Uptake of Sotrovimab for prevention of severe COVID-19 and its safety in the community in England

Impact of vaccination on COVID-19-associated admissions to critical care in England: a population cohort study of linked data

Ethnicity and risks of severe COVID-19 outcomes associated with glucose-lowering medications: A cohort study

Oxcode Symposium Poster Weiqi Liao Qcancer2 DART

Oxcode Symposium Lightning Talk Weiqi Liao Qcancer2 DART (WP6)

QCovid 4 - Predicting risk of death or hospitalisation from COVID-19 in adults testing positive for SARS-CoV-2 infection during the Omicron wave in England

Risk of Myocarditis After Sequential Doses of COVID-19 Vaccine and SARS-CoV-2 Infection by Age and Sex

Identifying key signs of motor neurone disease in primary care: a nested case–control study using the QResearch database

Development and validation of a meta-learner for combining statistical and machine learning prediction models in individuals with depression

Associations of BMI with COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes after vaccination in England: a population-based cohort study

Temporality of body mass index, blood tests, comorbidities and medication use as early markers for pancreatic ductal adenocarcinoma (PDAC): a nested case–control study

Common protocol for validation of the QCOVID algorithm across the four UK nations

Predicting the future risk of lung cancer: development and validation of QCancer2 (10-year risk) lung model and evaluating the model performance of nine prediction models

Neuropsychiatric Ramifications of Severe COVID-19 and Other Severe Acute Respiratory Infections

Childhood, teenage and young adult cancer diagnosis during the first wave of the COVID-19 pandemic: a population-based observational cohort study in England

Development and validation of clinical prediction models for breast cancer incidence and mortality: a protocol for a dual cohort study

Association between smoking, e-cigarette use and severe COVID-19: a cohort study

Lifestyle advice for hypertension or diabetes: trend analysis from 2002 to 2017 in England

Validating the QCOVID risk prediction algorithm for risk of mortality from COVID-19 in the adult population in Wales, UK

Analysis of incidence of motor neuron disease in England 1998–2019: use of three linked datasets

Development, validation, and evaluation of prediction models to identify individuals at high risk of lung cancer for screening in the English primary care population using the QResearch® database: research protocol and statistical analysis plan.

Risk of myocarditis following sequential COVID-19 vaccinations by age and sex

Predicting risk of pancreatic cancer in individuals with new-onset type-2 diabetes in primary care: protocol for the development and validation of a clinical prediction model (QPancreasD)

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection

QCOVID in Scotland: time to recalibrate our expectations?

External validation of the QCovid risk prediction algorithm for risk of COVID-19 hospitalisation and mortality in adults: national validation cohort study in Scotland

Neurological complications after first dose of COVID-19 vaccines and SARS-CoV-2 infection

Use of menopausal hormone therapy and risk of dementia: nested case-control studies using QResearch and CPRD databases

Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: national prospective cohort study

Identifying symptoms associated with diagnosis of pancreatic exocrine and neuroendocrine neoplasms: a nested case-control study of the UK primary care population

OX79 Qresearch ICNARC Covid-19 psychological outcomes

Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study

Hormone replacement therapy and cancer survival: a longitudinal cohort study: protocol paper

Sickle-cell disorders and severe COVID-19 outcomes: a cohort study

Mortality and critical care unit admission associated with the SARS-CoV-2 lineage B.1.1.7 in England: an observational cohort study

Association Between Race and COVID-19 Outcomes Among 2.6 Million Children in England

External validation of a model to predict women most at risk of postpartum venous thromboembolism: Maternity clot risk

An external validation of the QCovid risk prediction algorithm for risk of mortality from COVID-19 in adults: a national validation cohort study in England

Associations between body-mass index and COVID-19 severity in 6·9 million people in England: a prospective, community-based, cohort study

Predicting the risk of prostate cancer in asymptomatic men: a cohort study to develop and validate a novel algorithm

Development and validation of QMortality risk prediction algorithm to estimate short term risk of death and assess frailty: cohort study